Šablon:UEFA Liga prvaka 2018/19 - 1/8
Prve utakmice odigrane su 12, 13, 19. i 20. februara, a uzvratne 5, 6, 12. i 13. marta 2019.
| Tim 1 | Rez. | Tim 2 | Prva utakmica | Druga utakmica |
|---|---|---|---|---|
Schalke 04 
|
2-10 |  Manchester City
|
2–3 | 0-7 |
Atlético Madrid 
|
2-3 |  Juventus
|
2–0 | 0-3 |
| Manchester United
|
3–3 (a) |  Paris Saint-Germain
|
0–2 | 3–1 |
| Tottenham Hotspur
|
4–0 | Borussia Dortmund
|
3–0 | 1–0 |
| Lyon
|
1–5 | Barcelona
|
0–0 | 1–5 |
| AS Roma
|
3–4 |  Porto
|
2–1 | 1–3 (a.e.t.) |
AFC Ajax 
|
5–3 | Real Madrid
|
1–2 | 4–1 |
| Liverpool
|
3–1 | Bayern München
|
0–0 | 3–1 |