AAGAB

AAGAB
Identifikatori
Aliasi	AAGAB
Vanjski ID-jevi	OMIM: 614888 MGI: 1914189 HomoloGene: 11648 GeneCards: AAGAB
Lokacija gena (čovjek)
Hrom.	Hromosom 15 (čovjek)
Kraj	67,255,195 bp
Lokacija gena (miš)
Hrom.	Hromosom 9 (miš)
Kraj	63,551,870 bp
Obrazac RNK ekspresije
	; ;
	Više referentnih podataka o ekspresiji
Ontologija gena
Molekularna funkcija	• GO:0001948, GO:0016582 vezivanje za proteine;
Ćelijska komponenta	• citoplazma; • citosol; • nuclear speck;
Biološki proces	• protein transport;
	Izvori:Amigo / QuickGO
Ortolozi
	79719
	66939
	ENSG00000103591
	ENSMUSG00000037257
	Q6PD74
	Q8R2R3
	NM_001271885; NM_001271886; NM_024666
	NM_025857; NM_001357323
	NP_001258814; NP_001258815; NP_078942
	NP_080133; NP_001344252
	Wikipodaci
Pogledaj/uredi – čovjek	Pogledaj/uredi – miš

Alfa- i gama-adaptin vezani protein, znan i kao AAGAB, je ljudski gen.^[5]^[6]

Aminokiselinska sekvenca

Dužina polipeptidnog lanca je 315 aminokiselina, a molekulska težina 34 594 Da.^[7].

10	20	30	40	50
MAAGVPCALV	TSCSSVFSGD	QLVQHILGTE	DLIVEVTSND	AVRFYPWTID
NKYYSADINL	CVVPNKFLVT	AEIAESVQAF	VVYFDSTQKS	GLDSVSSWLP
LAKAWLPEVM	ILVCDRVSED	GINRQKAQEW	CIKHGFELVE	LSPEELPEED
DDFPESTGVK	RIVQALNANV	WSNVVMKNDR	NQGFSLLNSL	TGTNHSIGSA
DPCHPEQPHL	PAADSTESLS	DHRGGASNTT	DAQVDSIVDP	MLDLDIQELA
SLTTGGGDVE	NFERLFSKLK	EMKDKAATLP	HEQRKVHAEK	VAKAFWMAIG
GDRDEIEGLS	SDEEH

Simboli

C: Cistein
D: Asparaginska kiselina
E: Glutaminska kiselina
F: Fenilalanin
G: Glicin
H: Histidin
I: Izoleucin
K: Lizin
L: Leucin
M: Metionin
N: Asparagin
P: Prolin
Q: Glutamin
R: Arginin
S: Serin
T: Treonin
V: Valin
W: Triptofan
Y: Tirozin

Reference

1 2 3 GRCh38: Ensembl release 89: ENSG00000103591 - Ensembl, maj 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000037257 - Ensembl, maj 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: FLJ11506 hypothetical protein FLJ11506".
↑ Reference, Genetics Home. "AAGAB gene". Genetics Home Reference (jezik: engleski). Arhivirano s originala, 6. 12. 2017. Pristupljeno 24. 11. 2017.
↑ "UniProt, Q6PD74" (jezik: engleski). Pristupljeno 12. 7. 2021.

Dopunska literatura

Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.

[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000103591 - Ensembl, maj 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000037257 - Ensembl, maj 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: FLJ11506 hypothetical protein FLJ11506".

[6] Reference, Genetics Home. "AAGAB gene". Genetics Home Reference (jezik: engleski). Arhivirano s originala, 6. 12. 2017. Pristupljeno 24. 11. 2017.

[UniProt-7] "UniProt, Q6PD74" (jezik: engleski). Pristupljeno 12. 7. 2021.

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