ARHGAP44

ARHGAP44
Identifikatori
Aliasi	ARHGAP44
Vanjski ID-jevi	OMIM: 617716 MGI: 2144423 HomoloGene: 65284 GeneCards: ARHGAP44
Lokacija gena (čovjek) Hrom. Hromosom 17 (čovjek) Bend 17p12 Početak 12,789,498 bp Kraj 12,991,643 bp
Lokacija gena (miš) Hrom. Hromosom 11 (miš) Bend 11|11 B3 Početak 64,892,865 bp Kraj 65,053,787 bp
Ontologija gena Molekularna funkcija • GO:0001948, GO:0016582 vezivanje za proteine • phospholipid binding • GO:0005097, GO:0005099, GO:0005100 GTPase activator activity Ćelijska komponenta • citoplazma • reciklirajući endosom • citosol • međućelijske veze • endozom • dendritična kičma • projekcija ćelije • sinapsa • leading edge membrane • glutamatergic synapse • intracellular anatomical structure • GO:0097483, GO:0097481 postsynaptic density • presynaptic active zone Biološki proces • GO:0032320, GO:0032321, GO:0032855, GO:0043089, GO:0032854 positive regulation of GTPase activity • regulation of small GTPase mediated signal transduction • GO:0072468 Transdukcija signala • Egzocitoza • regulation of actin cytoskeleton organization • GO:0043087, GO:0032313, GO:0032319, GO:0032314, GO:0043088 regulation of GTPase activity • regulation of dendritic spine morphogenesis • modification of dendritic spine • neurotransmitter receptor transport, endosome to postsynaptic membrane • negative regulation of Rac protein signal transduction • modification of postsynaptic structure • regulation of neurotransmitter receptor transport, endosome to postsynaptic membrane Izvori:Amigo / QuickGO
Ortolozi
Vrste	Čovjek	Miš
Entrez	9912	216831
Ensembl	ENSG00000006740	ENSMUSG00000033389
UniProt	Q17R89	Q5SSM3
RefSeq (mRNK)	NM_014859 NM_001321164 NM_001321166 NM_001321167 NM_001321168	NM_001099288 NM_175003
RefSeq (bjelančevina)	NP_001308093 NP_001308095 NP_001308096 NP_001308097 NP_055674	NP_001092758 NP_778168 NP_001395152 NP_001395153 NP_001395155 NP_001395157
Lokacija (UCSC)	Chr 17: 12.79 – 12.99 Mb	Chr 11: 64.89 – 65.05 Mb
PubMed pretraga
Wikipodaci
Pogledaj/uredi – čovjek Pogledaj/uredi – miš

Rho GTPazno aktivirajući protein 44 jest protein koji je kod ljudi kodiran genom ARHGAP44.

Dužina polipeptidnog lanca je 818 aminokiselina, sa molekulskom težinom od 89.247.

Aminokiselinska sekvenca

Simboli

C: Cistein
D: Asparaginska kiselina
E: Glutaminska kiselina
F: Fenilalanin
G: Glicin
H: Histidin
I: Izoleucin
K: Lizin
L: Leucin
M: Metionin
N: Asparagin
P: Prolin
Q: Glutamin
R: Arginin
S: Serin
T: Treonin
V: Valin
W: Triptofan
Y: Tirozin

10		20		30		40		50
MKKQFNRMRQ		LANQTVGRAE		KTEVLSEDLL		QVEKRLELVK		QVSHSTHKKL
TACLQGQQGA		EADKRSKKLP		LTTLAQCLME		GSAILGDDTL		LGKMLKLCGE
TEDKLAQELI		HFELQVERDV		IEPLFLLAEV		EIPNIQKQRK		HLAKLVLDMD
SSRTRWQQTS		KSSGLSSSLQ		PAGAKADALR		EEMEEAANRV		EICRDQLSAD
MYSFVAKEID		YANYFQTLIE		VQAEYHRKSL		TLLQAVLPQI		KAQQEAWVEK
PSFGKPLEEH		LTISGREIAF		PIEACVTMLL		ECGMQEEGLF		RVAPSASKLK
KLKAALDCCV		VDVQEYSADP		HAIAGALKSY		LRELPEPLMT		FELYDEWIQA
SNVQEQDKKL		QALWNACEKL		PKANHNNIRY		LIKFLSKLSE		YQDVNKMTPS
NMAIVLGPNL		LWPQAEGNIT		EMMTTVSLQI		VGIIEPIIQH		ADWFFPGEIE
FNITGNYGSP		VHVNHNANYS		SMPSPDMDPA		DRRQPEQARR		PLSVATDNMM
LEFYKKDGLR		KIQSMGVRVM		DTNWVARRGS		SAGRKVSCAP		PSMQPPAPPA
ELAAPLPSPL		PEQPLDSPAA		PALSPSGLGL		QPGPERTSTT		KSKELSPGSA
QKGSPGSSQG		TACAGTQPGA		QPGAQPGASP		SPSQPPADQS		PHTLRKVSKK
LAPIPPKVPF		GQPGAMADQS		AGQPSPVSLS		PTPPSTPSPY		GLSYPQGYSL
ASGQLSPAAA		PPLASPSVFT		STLSKSRPTP		KPRQRPTLPP		PQPPTVNLSA
SSPQSTEAPM		LDGMSPGESM		STDLVHFDIP		SIHIELGSTL		RLSPLEHMRR
HSVTDKRDSE		EESESTAL