CDC123
| CDC123 | |||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||||||||||||||||||
| Aliasi | CDC123 | ||||||||||||||||||||||||
| Vanjski ID-jevi | OMIM: 617708 MGI: 2138811 HomoloGene: 4394 GeneCards: CDC123 | ||||||||||||||||||||||||
| |||||||||||||||||||||||||
| |||||||||||||||||||||||||
| |||||||||||||||||||||||||
| Ortolozi | |||||||||||||||||||||||||
| Vrste | Čovjek | Miš | |||||||||||||||||||||||
| Entrez | |||||||||||||||||||||||||
| Ensembl | |||||||||||||||||||||||||
| UniProt | |||||||||||||||||||||||||
| RefSeq (mRNK) | |||||||||||||||||||||||||
| RefSeq (bjelančevina) | |||||||||||||||||||||||||
| Lokacija (UCSC) | Chr 10: 12.2 – 12.25 Mb | Chr 2: 5.8 – 5.85 Mb | |||||||||||||||||||||||
| PubMed pretraga | [3] | [4] | |||||||||||||||||||||||
| Wikipodaci | |||||||||||||||||||||||||
| |||||||||||||||||||||||||
Homologni protein 123 ciklusa ćelijske diobe je protein koji je klod ljudi kodiran genom CDC123.[5][6]
Aminokiselinska sekvenca
[uredi | uredi izvor]Dužina polipeptidnog lanca je 336 aminokiselina, а molekulska težina 39.135[7]
| 10 | 20 | 30 | 40 | 50 | ||||
|---|---|---|---|---|---|---|---|---|
| MKKEHVLHCQ | FSAWYPFFRG | VTIKSVILPL | PQNVKDYLLD | DGTLVVSGRD | ||||
| DPPTHSQPDS | DDEAEEIQWS | DDENTATLTA | PEFPEFATKV | QEAINSLGGS | ||||
| VFPKLNWSAP | RDAYWIAMNS | SLKCKTLSDI | FLLFKSSDFI | TRDFTQPFIH | ||||
| CTDDSPDPCI | EYELVLRKWC | ELIPGAEFRC | FVKENKLIGI | SQRDYTQYYD | ||||
| HISKQKEEIR | RCIQDFFKKH | IQYKFLDEDF | VFDIYRDSRG | KVWLIDFNPF | ||||
| GEVTDSLLFT | WEELISENNL | NGDFSEVDAQ | EQDSPAFRCT | NSEVTVQPSP | ||||
| YLSYRLPKDF | VDLSTGEDAH | KLIDFLKLKR | NQQEDD |
Reference
[uredi | uredi izvor]- 1 2 3 GRCh38: Ensembl release 89: ENSG00000151465 - Ensembl, maj 2017
- 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000039128 - Ensembl, maj 2017
- ↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ↑ Bieganowski P, Shilinski K, Tsichlis PN, Brenner C (Oct 2004). "Cdc123 and checkpoint forkhead associated with RING proteins control the cell cycle by controlling eIF2gamma abundance". J Biol Chem. 279 (43): 44656–66. doi:10.1074/jbc.M406151200. PMID 15319434.
- ↑ "Entrez Gene: CDC123 cell division cycle 123 homolog (S. cerevisiae)".
- ↑ "UniProt, O75794". Pristupljeno 31. 8. 2021.
Dopunska literatura
[uredi | uredi izvor]- Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
- Okuda A, Kimura G (1996). "An amino acid change in novel protein D123 is responsible for temperature-sensitive G1-phase arrest in a mutant of rat fibroblast line 3Y1". Exp. Cell Res. 223 (2): 242–9. doi:10.1006/excr.1996.0078. PMID 8601400.
- Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
- Onisto M, Zeilante P, Scannapieco P, et al. (1998). "Expression study on D123 gene product: evidence for high positivity in testis". Exp. Cell Res. 242 (2): 451–9. doi:10.1006/excr.1998.4074. PMID 9683532.
- Hoja MR, Wahlestedt C, Höög C (2000). "A visual intracellular classification strategy for uncharacterized human proteins". Exp. Cell Res. 259 (1): 239–46. doi:10.1006/excr.2000.4948. PMID 10942595.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Deloukas P, Earthrowl ME, Grafham DV, et al. (2004). "The DNA sequence and comparative analysis of human chromosome 10". Nature. 429 (6990): 375–81. doi:10.1038/nature02462. PMID 15164054.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Vanjski linkovi
[uredi | uredi izvor]- Lokacija ljudskog genoma CDC123 i stranica sa detaljima o genu CDC123 u UCSC Genome Browseru.