DCUN1D4

DCUN1D4
Identifikatori
Aliasi	DCUN1D4
Vanjski ID-jevi	OMIM: 612977 MGI: 2140972 HomoloGene: 22867 GeneCards: DCUN1D4
Lokacija gena (čovjek)
Hrom.	Hromosom 4 (čovjek)
Kraj	51,916,837 bp
Lokacija gena (miš)
Hrom.	Hromosom 5 (miš)
Kraj	73,718,137 bp
Obrazac RNK ekspresije
	; ; ; ;
	Više referentnih podataka o ekspresiji
Ontologija gena
Molekularna funkcija	• cullin family protein binding; • ubiquitin-like protein binding; • GO:0001948, GO:0016582 vezivanje za proteine; • ubiquitin conjugating enzyme binding; • molekularna funkcija;
Ćelijska komponenta	• jedro; • kompleks ubikvitin-ligaze;
Biološki proces	• protein neddylation; • positive regulation of ubiquitin-protein transferase activity; • GO:0022610 biološki proces;
	Izvori:Amigo / QuickGO
Ortolozi
	23142
	100737
	ENSG00000109184
	ENSMUSG00000051674
	Q92564
	Q8CCA0
	NM_001040402; NM_001287755; NM_001287757; NM_015115
	NM_001190733; NM_001190734; NM_178896
	NP_001035492; NP_001274684; NP_001274686; NP_055930
	NP_001177662; NP_001177663; NP_849227
	Wikipodaci
Pogledaj/uredi – čovjek	Pogledaj/uredi – miš

DCN1-liki protein 4 jest protein koji je kod ljudi kodiran genom DCUN1D4 sa hromosoma 4.^[5]^[6]

Aminokiselinska sekvenca

Dužina polipeptidnog lanca je 292 aminokiseline, а molekulska težina 34.068 Da.^[7]

C: Cistein

D: Asparaginska kiselina

E: Glutaminska kiselina

F: Fenilalanin

G: Glicin

H: Histidin

I: Izoleucin

K: Lizin

L: Leucin

M: Metionin

N: Asparagin

P: Prolin

Q: Glutamin

R: Arginin

S: Serin

T: Treonin

V: Valin

W: Triptofan

Y: Tirozin

10	20	30	40	50
MHSDAAAVNF	QLNSHLSTLA	NIHKIYHTLN	KLNLTEDIGQ	DDHQTGSLRS
CSSSDCFNKV	MPPRKKRRPA	SGDDLSAKKS	RHDSMYRKYD	STRIKTEEEA
FSSKRCLEWF	YEYAGTDDVV	GPEGMEKFCE	DIGVEPENVV	MLVLAWKLDA
QNMGYFTLQE	WLKGMTSLQC	DTTEKLRNTL	DYLRSFLNDS	TNFKLIYRYA
FDFAREKDQR	SLDINTAKCM	LGLLLGKIWP	LFPVFHQFLE	QSKYKVINKD
QWCNVLEFSR	TINLDLSNYD	EDGAWPVLLD	EFVEWYKDKQ	MS

Reference

1 2 3 GRCh38: Ensembl release 89: ENSG00000109184 - Ensembl, maj 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000051674 - Ensembl, maj 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Kurz T, Ozlu N, Rudolf F, O'Rourke SM, Luke B, Hofmann K, Hyman AA, Bowerman B, Peter M (Jun 2005). "The conserved protein DCN-1/Dcn1p is required for cullin neddylation in C. elegans and S. cerevisiae". Nature. 435 (7046): 1257–61. doi:10.1038/nature03662. PMID 15988528. S2CID 4328225.
↑ "Entrez Gene: DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 (S. cerevisiae)".
↑ "UniProt, Q92564" (jezik: engleski). Pristupljeno 25. 10. 2021.

Dopunska literatura

Nagase T, Seki N, Ishikawa K, et al. (1997). "Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain". DNA Res. 3 (5): 321–9, 341–54. doi:10.1093/dnares/3.5.321. PMID 9039502.
Hartley JL, Temple GF, Brasch MA (2001). "DNA Cloning Using In Vitro Site-Specific Recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to Biology: A Functional Genomics Pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.

[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000109184 - Ensembl, maj 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000051674 - Ensembl, maj 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid15988528-5] Kurz T, Ozlu N, Rudolf F, O'Rourke SM, Luke B, Hofmann K, Hyman AA, Bowerman B, Peter M (Jun 2005). "The conserved protein DCN-1/Dcn1p is required for cullin neddylation in C. elegans and S. cerevisiae". Nature. 435 (7046): 1257–61. doi:10.1038/nature03662. PMID 15988528. S2CID 4328225.

[entrez-6] "Entrez Gene: DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 (S. cerevisiae)".

[UniProt-7] "UniProt, Q92564" (jezik: engleski). Pristupljeno 25. 10. 2021.

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