GYLTL1B
Glikoziltransferazoliki protein LARGE2 je enzim koji je kod ljudi kodiran genom GYLTL1B.[5][6][7]
Aminokiselinska sekvenca[uredi | uredi izvor]
Dužina polipeptidnog lanca je 721 aminokiselina, a molekulska težina 81.787 Da.[8].
| 10 | 20 | 30 | 40 | 50 | ||||
|---|---|---|---|---|---|---|---|---|
| MLPRGRPRAL | GAAALLLLLL | LLGFLLFGGD | LGCERREPGG | RAGAPGCFPG | ||||
| PLMPRVPPDG | RLRRAAALDG | DPGAGPGDHN | RSDCGPQPPP | PPKCELLHVA | ||||
| IVCAGHNSSR | DVITLVKSML | FYRKNPLHLH | LVTDAVARNI | LETLFHTWMV | ||||
| PAVRVSFYHA | DQLKPQVSWI | PNKHYSGLYG | LMKLVLPSAL | PAELARVIVL | ||||
| DTDVTFASDI | SELWALFAHF | SDTQAIGLVE | NQSDWYLGNL | WKNHRPWPAL | ||||
| GRGFNTGVIL | LRLDRLRQAG | WEQMWRLTAR | RELLSLPATS | LADQDIFNAV | ||||
| IKEHPGLVQR | LPCVWNVQLS | DHTLAERCYS | EASDLKVIHW | NSPKKLRVKN | ||||
| KHVEFFRNFY | LTFLEYDGNL | LRRELFVCPS | QPPPGAEQLQ | QALAQLDEED | ||||
| PCFEFRQQQL | TVHRVHVTFL | PHEPPPPRPH | DVTLVAQLSM | DRLQMLEALC | ||||
| RHWPGPMSLA | LYLTDAEAQQ | FLHFVEASPV | LAARQDVAYH | VVYREGPLYP | ||||
| VNQLRNVALA | QALTPYVFLS | DIDFLPAYSL | YDYLRASIEQ | LGLGSRRKAA | ||||
| LVVPAFETLR | YRFSFPHSKV | ELLALLDAGT | LYTFRYHEWP | RGHAPTDYAR | ||||
| WREAQAPYRV | QWAANYEPYV | VVPRDCPRYD | PRFVGFGWNK | VAHIVELDAQ | ||||
| EYELLVLPEA | FTIHLPHAPS | LDISRFRSSP | TYRDCLQALK | DEFHQDLSRH | ||||
| HGAAALKYLP | ALQQPQSPAR | G |
Reference[uredi | uredi izvor]
- ^ a b c GRCh38: Ensembl release 89: ENSG00000165905 - Ensembl, maj 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000040434 - Ensembl, maj 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Brockington M, Torelli S, Prandini P, Boito C, Dolatshad NF, Longman C, Brown SC, Muntoni F (Feb 2005). "Localization and functional analysis of the LARGE family of glycosyltransferases: significance for muscular dystrophy". Hum Mol Genet. 14 (5): 657–65. doi:10.1093/hmg/ddi062. PMID 15661757.
- ^ Grewal PK, McLaughlan JM, Moore CJ, Browning CA, Hewitt JE (Sep 2005). "Characterization of the LARGE family of putative glycosyltransferases associated with dystroglycanopathies". Glycobiology. 15 (10): 912–23. doi:10.1093/glycob/cwi094. PMID 15958417.
- ^ "Entrez Gene: GYLTL1B glycosyltransferase-like 1B".
- ^ "UniProt, Q8N3Y3". Pristupljeno 22. 8. 2021.
Dopunska literatura[uredi | uredi izvor]
- Oh JH, Yang JO, Hahn Y, et al. (2006). "Transcriptome analysis of human gastric cancer". Mamm. Genome. 16 (12): 942–54. doi:10.1007/s00335-005-0075-2. PMID 16341674. S2CID 69278.
- Fujimura K, Sawaki H, Sakai T, et al. (2005). "LARGE2 facilitates the maturation of alpha-dystroglycan more effectively than LARGE". Biochem. Biophys. Res. Commun. 329 (3): 1162–71. doi:10.1016/j.bbrc.2005.02.082. PMID 15752776.
- Wan D, Gong Y, Qin W, et al. (2004). "Large-scale cDNA transfection screening for genes related to cancer development and progression". Proc. Natl. Acad. Sci. U.S.A. 101 (44): 15724–9. doi:10.1073/pnas.0404089101. PMC 524842. PMID 15498874.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.