LY6G6E
(Preusmjereno sa Lokus G6E kompleksa limfocitnog antigena 6)
| LY6G6E | |||||||
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| Identifikatori | |||||||
| Aliasi | LY6G6E | ||||||
| Vanjski ID-jevi | OMIM: 610437 GeneCards: LY6G6E | ||||||
| Ortolozi | |||||||
| Vrste | Čovjek | Miš | |||||
| Entrez |
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| Ensembl |
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| RefSeq (mRNK) |
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| RefSeq (bjelančevina) |
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| Lokacija (UCSC) | n/a | n/a | |||||
| PubMed pretraga | [1] | n/a | |||||
| Wikipodaci | |||||||
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Lokus G6E kompleksa limfocitnog antigena 6 (pseudogen) jest protein koji je kod ljudi kodiran genom LY6G6E.[2]
Funkcija
[uredi | uredi izvor]LY6G6E pripada klasteru gena leukocitnog antigena-6 (LY6) koji se nalazi u glavnom kompleksu histokompatibilnosti (MHC) klase III, na hromosomu 6. Članovi LY6 natporodice obično sadrže 70 do 80 aminokiselina, uključujući osam do 10 cisteina. |Većina proteina LY6 vezana je za ćelijsku površinu pomoću glikozilfosfatidilinozitola (GPI) sidra koje je direktno uključeno u transdukciju signala.[3]
Reference
[uredi | uredi izvor]- ↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ↑ "Entrez Gene: Lymphocyte antigen 6 complex, locus G6E pseudogene)".
- ↑ Mallya M, Campbell RD, Aguado B (juli 2002). "Transcriptional analysis of a novel cluster of LY-6 family members in the human and mouse major histocompatibility complex: five genes with many splice forms". Genomics. 80 (1): 113–23. doi:10.1006/geno.2002.6794. PMID 12079290.
Dopunska literatura
[uredi | uredi izvor]- Mallya M, Campbell RD, Aguado B (oktobar 2006). "Characterization of the five novel Ly-6 superfamily members encoded in the MHC, and detection of cells expressing their potential ligands". Protein Science. 15 (10): 2244–56. doi:10.1110/ps.062242606. PMC 2242401. PMID 17008713.
- Ribas G, Neville M, Wixon JL, Cheng J, Campbell RD (juli 1999). "Genes encoding three new members of the leukocyte antigen 6 superfamily and a novel member of Ig superfamily, together with genes encoding the regulatory nuclear chloride ion channel protein (hRNCC) and an N omega-N omega-dimethylarginine dimethylaminohydrolase homologue, are found in a 30-kb segment of the MHC class III region". Journal of Immunology. 163 (1): 278–87. PMID 10384126.
- Vignal C, Bansal AT, Balding DJ, Binks MH, Dickson MC, Montgomery DS, Wilson AG (januar 2009). "Genetic association of the major histocompatibility complex with rheumatoid arthritis implicates two non-DRB1 loci". Arthritis and Rheumatism. 60 (1): 53–62. doi:10.1002/art.24138. PMID 19116923.
- "Complete sequence and gene map of a human major histocompatibility complex. The MHC sequencing consortium". Nature. 401 (6756): 921–3. oktobar 1999. doi:10.1038/44853. PMID 10553908. S2CID 186243515.