MTP18

MTP18
Identifikatori
Aliasi	MTFP1
Vanjski ID-jevi	OMIM: 610235 MGI: 1916686 HomoloGene: 32318 GeneCards: MTFP1
Lokacija gena (čovjek) Hrom. Hromosom 22 (čovjek) Bend 22q12.2 Početak 30,425,623 bp Kraj 30,429,054 bp
Lokacija gena (miš) Hrom. Hromosom 11 (miš) Bend 11|11 A1 Početak 4,041,480 bp Kraj 4,045,445 bp
Ortolozi
Vrste	Čovjek	Miš
Entrez	51537	67900
Ensembl	ENSG00000242114	ENSMUSG00000004748
UniProt	Q9UDX5	Q9CRB8
RefSeq (mRNK)	NM_016498 NM_001003704	NM_026443
RefSeq (bjelančevina)	NP_001003704 NP_057582	NP_080719
Lokacija (UCSC)	Chr 22: 30.43 – 30.43 Mb	Chr 11: 4.04 – 4.05 Mb
PubMed pretraga
Wikipodaci
Pogledaj/uredi – čovjek Pogledaj/uredi – miš

Mitohondrijski protein od 18 kDa, znan i kao MTP18, ljudski genom sa hromosoma 22.

Aminokiselinska sekvenca

Dužina polipeptidnog lanca je 166 aminokiseline, a molekulska težina 18.010 Da.

• C: Cistein
• D: Asparaginska kiselina
• E: Glutaminska kiselina
• F: Fenilalanin
• G: Glicin
• H: Histidin
• I: Izoleucin
• K: Lizin
• L: Leucin
• M: Metionin
• N: Asparagin
• P: Prolin
• Q: Glutamin
• R: Arginin
• S: Serin
• T: Treonin
• V: Valin
• W: Triptofan
• Y: Tirozin

10		20		30		40		50
MSEPQPRGAE		RDLYRDTWVR		YLGYANEVGE		AFRSLVPAAV		VWLSYGVASS
YVLADAIDKG		KKAGEVPSPE		AGRSARVTVA		VVDTFVWQAL		ASVAIPGFTI
NRVCAASLYV		LGTATRWPLA		VRKWTTTALG		LLTIPIIIHP		IDRSVDFLLD
SSLRKLYPTV		GKPSSS

Dopunska literatura

• Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.
• Sanger Centre, The; Washington University Genome Sequencing Cente, The (1999). "Toward a complete human genome sequence". Genome Res. 8 (11): 1097–108. doi:10.1101/gr.8.11.1097. PMID 9847074.
• Dunham I, Shimizu N, Roe BA, et al. (1999). "The DNA sequence of human chromosome 22". Nature. 402 (6761): 489–95. Bibcode:1999Natur.402..489D. doi:10.1038/990031. PMID 10591208.
• Zhang QH, Ye M, Wu XY, et al. (2001). "Cloning and Functional Analysis of cDNAs with Open Reading Frames for 300 Previously Undefined Genes Expressed in CD34+ Hematopoietic Stem/Progenitor Cells". Genome Res. 10 (10): 1546–60. doi:10.1101/gr.140200. PMC 310934. PMID 11042152.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Tondera D, Santel A, Schwarzer R, et al. (2004). "Knockdown of MTP18, a novel phosphatidylinositol 3-kinase-dependent protein, affects mitochondrial morphology and induces apoptosis". J. Biol. Chem. 279 (30): 31544–55. doi:10.1074/jbc.M404704200. PMID 15155745.
• Collins JE, Wright CL, Edwards CA, et al. (2005). "A genome annotation-driven approach to cloning the human ORFeome". Genome Biol. 5 (10): R84. doi:10.1186/gb-2004-5-10-r84. PMC 545604. PMID 15461802.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Cheng J, Kapranov P, Drenkow J, et al. (2005). "Transcriptional maps of 10 human chromosomes at 5-nucleotide resolution". Science. 308 (5725): 1149–54. Bibcode:2005Sci...308.1149C. doi:10.1126/science.1108625. PMID 15790807. S2CID 13047538.
• Kapranov P, Drenkow J, Cheng J, et al. (2005). "Examples of the complex architecture of the human transcriptome revealed by RACE and high-density tiling arrays". Genome Res. 15 (7): 987–97. doi:10.1101/gr.3455305. PMC 1172043. PMID 15998911.