RPL37A
60S ribosomki protein L37a jest protein koji je kod ljudi kodiran genom sa hromosoma 2.
Amiokiselininska sekvenca[uredi | uredi izvor]
Dužina polipeptidnog lanca je aminokiselina, a molekulska težina Da.
Ovo je protein koji je kod ljudi kodiran genom RPL37A'.[5][6]
Eunkcija[uredi | uredi izvor]
Ribozomi, organele koje katalizuju sintezu proteina, sastoje se od male 40S podjedinice i velike 60S podjedinice. Ove podjedinice zajedno se sastoje od čerirein tio SadržWE četirim tipa RNK i otprilike 80 strukturno različitih proteina. Ovaj gen kodira ribosomski protein koji je komponenta 60S podjedinice. Protein pripada porodici ribosomskih proteina L37AE. Nalazi se u citoplazmi. Protein sadrži domen nalik na cinkov prst tipa C4. Kao što je tipSLo za gene koji kodiraju ribosomske proteine, postoji više obrađenih pseudogena ovog gena dispergiranih kroz genom.[6]
Reference[uredi | uredi izvor]
- ^ a b c GRCh38: Ensembl release 89: ENSG00000197756 - Ensembl, maj 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000046330 - Ensembl, maj 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Hoof T, Fislage R, Tummler B (Dec 1992). "Primary sequence of the human ribosomal protein L37a". Nucleic Acids Res. 20 (20): 5475. doi:10.1093/nar/20.20.5475. PMC 334360. PMID 1437567.
- ^ a b "Entrez Gene: RPL37A ribosomal protein L37a".
Dopumska literatura[uredi | uredi izvor]
- Wool IG, Chan YL, Glück A (1996). "Structure and evolution of mammalian ribosomal proteins". Biochem. Cell Biol. 73 (11–12): 933–47. doi:10.1139/o95-101. PMID 8722009.
- Kato S, Sekine S, Oh SW, et al. (1995). "Construction of a human full-length cDNA bank". Gene. 150 (2): 243–50. doi:10.1016/0378-1119(94)90433-2. PMID 7821789.
- Saha DP, Tirumalai PS, Scala LA, Howells RD (1993). "Human ribosomal protein L37a: cloning of the cDNA and analysis of differential gene expression in tissues and cell lines". Gene. 132 (2): 285–9. doi:10.1016/0378-1119(93)90209-L. PMID 8224875.
- Uechi T, Tanaka T, Kenmochi N (2001). "A complete map of the human ribosomal protein genes: assignment of 80 genes to the cytogenetic map and implications for human disorders". Genomics. 72 (3): 223–30. doi:10.1006/geno.2000.6470. PMID 11401437.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Odintsova TI, Müller EC, Ivanov AV, et al. (2004). "Characterization and analysis of posttranslational modifications of the human large cytoplasmic ribosomal subunit proteins by mass spectrometry and Edman sequencing". J. Protein Chem. 22 (3): 249–58. doi:10.1023/A:1025068419698. PMID 12962325. S2CID 10710245.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.
linovi[uredi | uredi izvor]
Amiokiselininska sekvenca[uredi | uredi izvor]
Dužina polipeptidnog lanca je aminokiselina, a molekulska težina Da.