RWDD2B

RWDD2B
Dostupne strukture
PDB	Pretraga ortologa: PDBe RCSB
Spisak PDB ID kodova
	2DAX
Identifikatori
Aliasi	RWDD2B
Vanjski ID-jevi	OMIM: 617843 MGI: 1858215 HomoloGene: 9654 GeneCards: RWDD2B
Lokacija gena (čovjek)
Hrom.	Hromosom 21 (čovjek)
Kraj	29,019,360 bp
Lokacija gena (miš)
Hrom.	Hromosom 16 (miš)
Kraj	87,237,461 bp
Obrazac RNK ekspresije
	Više referentnih podataka o ekspresiji
Ontologija gena
Molekularna funkcija	• GO:0001948, GO:0016582 vezivanje za proteine; • molekularna funkcija;
Ćelijska komponenta	• ćelijska komponenta;
Biološki proces	• GO:0022610 biološki proces;
	Izvori:Amigo / QuickGO
Ortolozi
	10069
	53858
	ENSG00000156253
	ENSMUSG00000041079
	P57060
	Q99M03
	NM_016940; NM_001320724
	NM_016924
	NP_001307653; NP_058636
	NP_058620
	Wikipodaci
Pogledaj/uredi – čovjek	Pogledaj/uredi – miš

Protein 2B sa domenom RWD jest protein koji je kod ljudi kodiran genom RWDD2B sa hromosoma 21.^[5]^[6]

Aminokiselinska sekvenca[uredi | uredi izvor]

Dužina polipeptidnog lanca je 319 aminokiselina, a molekulska težina 36 332 Da.^[6]

C: Cistein

D: Asparaginska kiselina

E: Glutaminska kiselina

F: Fenilalanin

G: Glicin

H: Histidin

I: Izoleucin

K: Lizin

L: Leucin

M: Metionin

N: Asparagin

P: Prolin

Q: Glutamin

R: Arginin

S: Serin

T: Treonin

V: Valin

W: Triptofan

Y: Tirozin

10	20	30	40	50
MKIELSMQPW	NPGYSSEGAT	AQETYTCPKM	IEMEQAEAQL	AELDLLASMF
PGENELIVND	QLAVAELKDC	IEKKTMEGRS	SKVYFTINMN	LDVSDEKMAM
FSLACILPFK	YPAVLPEITV	RSVLLSRSQQ	TQLNTDLTAF	LQKHCHGDVC
ILNATEWVRE	HASGYVSRDT	SSSPTTGSTV	QSVDLIFTRL	WIYSHHIYNK
CKRKNILEWA	KELSLSGFSM	PGKPGVVCVE	GPQSACEEFW	SRLRKLNWKR
ILIRHREDIP	FDGTNDETER	QRKFSIFEEK	VFSVNGARGN	HMDFGQLYQF
LNTKGCGDVF	QMFFGVEGQ

Reference[uredi | uredi izvor]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000156253 - Ensembl, maj 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000041079 - Ensembl, maj 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Orti R, Rachidi M, Vialard F, Toyama K, Lopes C, Taudien S, Rosenthal A, Yaspo ML, Sinet PM, Delabar JM (May 2000). "Characterization of a novel gene, C21orf6, mapping to a critical region of chromosome 21q22.1 involved in the monosomy 21 phenotype and of its murine ortholog, orf5". Genomics. 64 (2): 203–10. doi:10.1006/geno.1999.6109. PMID 10729227.
^ ^a ^b "Entrez Gene: C21orf6 chromosome 21 open reading frame 6".

Dopunska literatura[uredi | uredi izvor]

Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Hattori M, Fujiyama A, Taylor TD, et al. (2000). "The DNA sequence of human chromosome 21". Nature. 405 (6784): 311–9. Bibcode:2000Natur.405..311H. doi:10.1038/35012518. PMID 10830953.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.

Vanjski linkovi[uredi | uredi izvor]

RWDD2B lokacija ljudskog genoma UCSC Genome Browser.

RWDD2B detalji ljudskog genoma u UCSC Genome Browser.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000156253 - Ensembl, maj 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000041079 - Ensembl, maj 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid10729227-5] Orti R, Rachidi M, Vialard F, Toyama K, Lopes C, Taudien S, Rosenthal A, Yaspo ML, Sinet PM, Delabar JM (May 2000). "Characterization of a novel gene, C21orf6, mapping to a critical region of chromosome 21q22.1 involved in the monosomy 21 phenotype and of its murine ortholog, orf5". Genomics. 64 (2): 203–10. doi:10.1006/geno.1999.6109. PMID 10729227.

[entrez-6] "Entrez Gene: C21orf6 chromosome 21 open reading frame 6".

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