TMEM109

TMEM109
Identifikatori
Aliasi	TMEM109
Vanjski ID-jevi	MGI: 1915789 HomoloGene: 11458 GeneCards: TMEM109
Lokacija gena (čovjek)
Hrom.	Hromosom 11 (čovjek)
Kraj	60,923,443 bp
Lokacija gena (miš)
Hrom.	Hromosom 19 (miš)
Kraj	10,859,365 bp
Ontologija gena
Molekularna funkcija	• voltage-gated ion channel activity; • molekularna funkcija; • GO:0001948, GO:0016582 vezivanje za proteine;
Ćelijska komponenta	• sarcoplasmic reticulum membrane; • Egzosom; • endoplasmic reticulum membrane; • jedro; • membrana; • Sarkoplazmatski retikulum; • nuclear outer membrane; • integral component of membrane; • Endoplazmatski retikulum;
Biološki proces	• ion transport; • negative regulation of cell death; • cellular response to gamma radiation; • intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; • regulation of ion transmembrane transport; • GO:0015915 transport; • ion transmembrane transport;
	Izvori:Amigo / QuickGO
Ortolozi
	79073
	68539
	ENSG00000110108
	ENSMUSG00000034659
	Q9BVC6
	Q3UBX0
	NM_024092
	NM_134142
	NP_076997
	NP_598903
	Wikipodaci
Pogledaj/uredi – čovjek	Pogledaj/uredi – miš

Ovaj protein tvori kationski ionski kanal u membrani endoplazmatskog retikuluma, skupljajući šest identičnih podjedinica.^[7]

Reference[uredi | uredi izvor]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000110108 - Ensembl, maj 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000034659 - Ensembl, maj 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: Transmembrane protein 109". Pristupljeno 2. 7. 2016.
^ "UniProt, Q9BVC6". Pristupljeno 28. 8. 2021.
^ Venturi, Elisa; Mio, Kazuhiro; Nishi, Miyuki; Ogura, Toshihiko; Moriya, Toshio; Pitt, Samantha J.; Okuda, Kazutaka; Kakizawa, Sho; Sitsapesan, Rebecca; Sato, Chikara; Takeshima, Hiroshi (2011). "Mitsugumin 23 Forms a Massive Bowl-Shaped Assembly and Cation-Conducting Channel". Biochemistry. 50 (13): 2623–2632. doi:10.1021/bi1019447. ISSN 0006-2960.

Yamazaki T, Sasaki N, Nishi M, Takeshima H (2010). "Facilitation of DNA damage-induced apoptosis by endoplasmic reticulum protein mitsugumin23". Biochem. Biophys. Res. Commun. 392 (2): 196–200. doi:10.1016/j.bbrc.2010.01.013. PMID 20060811.