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Sindetin

S Wikipedije, slobodne enciklopedije
(Preusmjereno sa VPS54L)
Sindetin
Identifikatori
AliasiVPS50
Vanjski ID-jeviOMIM: 616465 MGI: 1920538 HomoloGene: 11498 GeneCards: VPS50
Lokacija gena (čovjek)
Hromosom 7 (čovjek)
Hrom.Hromosom 7 (čovjek)[1]
Hromosom 7 (čovjek)
Genomska lokacija za Sindetin
Genomska lokacija za Sindetin
Bend7q21.2-q21.3Početak93,232,340 bp[1]
Kraj93,361,123 bp[1]
Lokacija gena (miš)
Hromosom 6 (miš)
Hrom.Hromosom 6 (miš)[2]
Hromosom 6 (miš)
Genomska lokacija za Sindetin
Genomska lokacija za Sindetin
Bend6|6 A1Početak3,498,382 bp[2]
Kraj3,603,531 bp[2]
Ontologija gena
Molekularna funkcija SNARE binding
GO:0001948, GO:0016582 vezivanje za proteine
Ćelijska komponenta reciklirajući endosom
EARP complex
endozom
Egzosom
membrana
citosol
Biološki proces protein transport
retrograde transport, endosome to Golgi
endocytic recycling
GO:0015915 transport
Izvori:Amigo / QuickGO
Ortolozi
VrsteČovjekMiš
Entrez
Ensembl
UniProt
RefSeq (mRNK)

NM_001257998
NM_017667
NM_024553

NM_001167750
NM_001167751
NM_024260

RefSeq (bjelančevina)

NP_001244927
NP_060137
NP_078829

NP_001161222
NP_001161223
NP_077222

Lokacija (UCSC)Chr 7: 93.23 – 93.36 MbChr 6: 3.5 – 3.6 Mb
PubMed pretraga[3][4]
Wikipodaci
Pogledaj/uredi – čovjekPogledaj/uredi – miš

Sindetin je protein koji je kod ljudi kodiran genom VPS50. Komponenta je EARP kompleksa koji je uključen u endocitnu reciklažu.[5]

Reference

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  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000004766 - Ensembl, maj 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000001376 - Ensembl, maj 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Schindler C, Chen Y, Pu J, Guo X, Bonifacino JS (2015). "EARP is a multisubunit tethering complex involved in endocytic recycling". Nature Cell Biology. 17 (5): 639–50. doi:10.1038/ncb3129. PMC 4417048. PMID 25799061.

Vanjski linkovi

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Literatura

[uredi | uredi izvor]
  • Bastian08: Bastian F, Parmentier G, Roux J, Moretti S, Laudet V, Robinson-Rechavi M (2008). "Bgee: Integrating and Comparing Heterogeneous Transcriptome Data Among Species." Data Integration in the Life Sciences. DILS 2008. Lecture Notes in Computer Science, vol 5109.
  • Bian14: Bian Y, Song C, Cheng K, Dong M, Wang F, Huang J, Sun D, Wang L, Ye M, Zou H (2014). "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome." J Proteomics 96;253-62. PMID 24275569
  • Canestri: Canestri F "A proposed clinical application of a model of CO2 laser radiation induced damage craters." J Med Eng Technol 12(3);112-7. PMID 3172165
  • Chen12b: Chen WH, Minguez P, Lercher MJ, Bork P (2012). "OGEE: an online gene essentiality database." Nucleic Acids Res 40(Database issue);D901-6. PMID 22075992
  • Daub08: Daub H, Olsen JV, Bairlein M, Gnad F, Oppermann FS, Korner R, Greff Z, Keri G, Stemmann O, Mann M (2008). "Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle." Mol Cell 31(3);438-48. PMID 18691976
  • Dephoure08: Dephoure N, Zhou C, Villen J, Beausoleil SA, Bakalarski CE, Elledge SJ, Gygi SP (2008). "A quantitative atlas of mitotic phosphorylation." Proc Natl Acad Sci U S A 105(31);10762-7. PMID 18669648