WASHC2C
Podjedinica 2C kompleksa WASH jest protein koji je kod ljudi kodiran genom WASHC2C.[5]
Aminokiselinska sekvenca[uredi | uredi izvor]
Dužina polipeptidnog lanca je 1.318 aminokiselina, a molekulska težina 144.668[6]
| 10 | 20 | 30 | 40 | 50 | ||||
|---|---|---|---|---|---|---|---|---|
| MMNRTTPDQE | LVPASEPVWE | RPWSVEEIRR | SSQSWSLAAD | AGLLQFLQEF | ||||
| SQQTISRTHE | IKKQVDGLIR | ETKATDCRLH | NVFNDFLMLS | NTQFIENRVY | ||||
| DEEVEEPVLK | AEAEKTEQEK | TREQKEVDLI | PKVQEAVNYG | LQVLDSAFEQ | ||||
| LDIKAGNSDS | EEDDANGRVE | LILEPKDLYI | DRPLPYLIGS | KLFMEQEDVG | ||||
| LGELSSEEGS | VGSDRGSIVD | TEEEKEEEES | DEDFAHHSDN | EQNQHTTQMS | ||||
| DEEEDDDGCD | LFADSEKEEE | DIEDIEENTR | PKRSRPTSFA | DELAARIKGD | ||||
| AMGRVDEEPT | TLPSGEAKPR | KTLKEKKERR | TPSDDEEDNL | FAPPKLTDED | ||||
| FSPFGSGGGL | FSGGKGLFDD | EDEESDLFTE | ASQDRQAGAS | VKEESSSSKP | ||||
| GKKIPAGAVS | VFLGDTDVFG | AASVPSLKEP | QKPEQPTPRK | SPYGPPPTGL | ||||
| FDDDDGDDDD | DFFSAPHSKP | SKTRKVQSTA | DIFGDEEGDL | FKEKAVASPE | ||||
| ATVSQTDENK | ARAEKKVTLS | YSKNLKPSSE | TKTQKGLFSD | EEDSEDLFSS | ||||
| QSASNLKGAS | LLPGKLPTSV | SLFDDEDEED | NLFGGTAAKK | QTLSLQAQRE | ||||
| EKAKASELSK | KKASALLFSS | DEEWNIPASQ | THLASDSRSK | GEPRDSGTLQ | ||||
| SQEAKAVKKT | SLFEEDKEDD | LFAIAKDSQK | KTQRVSLLFE | DDVDSGGSLF | ||||
| GSPPTSVPPA | TKKKETVSEA | PPLLFSDEEE | KEAQLGVKSV | DKKVESAKES | ||||
| LKFGRTDVAE | SEKEGLLTRS | AQETVKHSDL | FSSSSPWDKG | TKPRTKTVLS | ||||
| LFDEEEDKME | DQNIIQAPQK | EVGKGCDPDA | HPKSTGVFQD | EELLFSHKLQ | ||||
| KDNDPDVDLF | AGTKKTKLLE | PSVGSLFGDD | EDDDLFSSAK | SQPLVQEKKR | ||||
| VVKKDHSVNS | FKNQKHPESI | QGSKEKGIWK | PETPQANLAI | NPAALLPTAA | ||||
| SQISEVKPVL | PELAFPSSEH | RRSHGLESVP | VLPGSGEAGV | SFDLPAQADT | ||||
| LHSANKSRVK | MRGKRRPQTR | AARRLAAQES | SEAEDMSVPR | GPIAQWADGA | ||||
| ISPNGHRPQL | RAASGEDSTE | EALAAAAAPW | EGGPVPGVDT | SPFAKSLGHS | ||||
| RGEADLFDSG | DIFSTGTGSQ | SVERTKPKAK | IAENPANPPV | GGKAKSPMFP | ||||
| ALGEASSDDD | LFQSAKPKPA | KKTNPFPLLE | DEDDLFTDQK | VKKNETKSSS | ||||
| QQDVILTTQD | IFEDDIFATE | AIKPSQKTRE | KEKTLESNLF | DDNIDIFADL | ||||
| TVKPKEKSKK | KVEAKSIFDD | DMDDIFSTGI | QAKTTKPKSR | SAQAAPEPRF | ||||
| EHKVSNIFDD | PLNAFGGQ |
Reference[uredi | uredi izvor]
- ^ a b c GRCh38: Ensembl release 89: ENSG00000172661 - Ensembl, maj 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000024104 - Ensembl, maj 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Entrez Gene: FAM21C family with sequence similarity 21, member C".
- ^ "UniProt, Q9Y4E1". Pristupljeno 31. 8. 2021.
Dopunska literatura[uredi | uredi izvor]
- Nagase T, Ishikawa K, Miyajima N, et al. (1998). "Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro". DNA Res. 5 (1): 31–9. doi:10.1093/dnares/5.1.31. PMID 9628581.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Brill LM, Salomon AR, Ficarro SB, et al. (2004). "Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry". Anal. Chem. 76 (10): 2763–72. doi:10.1021/ac035352d. PMID 15144186.
- Deloukas P, Earthrowl ME, Grafham DV, et al. (2004). "The DNA sequence and comparative analysis of human chromosome 10". Nature. 429 (6990): 375–81. doi:10.1038/nature02462. PMID 15164054.
- Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Lim J, Hao T, Shaw C, et al. (2006). "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration". Cell. 125 (4): 801–14. doi:10.1016/j.cell.2006.03.032. PMID 16713569. S2CID 13709685.
- Beausoleil SA, Villén J, Gerber SA, et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nat. Biotechnol. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID 16964243. S2CID 14294292.
- Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.