ZNF268

S Wikipedije, slobodne enciklopedije
ZNF268
Dostupne strukture
PDBPretraga Human UniProta: PDBe RCSB
Spisak PDB ID kodova

2EL4, 2EL5, 2EL6, 2EM1, 2EMV, 2EMW, 2EMX, 2EMY, 2EN0, 2EN6, 2EN7, 2EOF, 2EOG, 2EOI, 2EOJ, 2EOK, 2EOL, 2EOP, 2EPV, 2EPW, 2EPY, 2YTF, 2YTQ

Identifikatori
AliasiZNF268
Vanjski ID-jeviOMIM: 604753 HomoloGene: 124392 GeneCards: ZNF268
Lokacija gena (čovjek)
Hromosom 12 (čovjek)
Hrom.Hromosom 12 (čovjek)[1]
Hromosom 12 (čovjek)
Genomska lokacija za ZNF268
Genomska lokacija za ZNF268
Bend12q24.33Početak133,181,409 bp[1]
Kraj133,214,832 bp[1]
Ontologija gena
Molekularna funkcija nucleic acid binding
DNA binding
GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity
metal ion binding
GO:0001948, GO:0016582 protein binding
GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific
Ćelijska komponenta intracellular anatomical structure
citoplazma
actin cytoskeleton
Jedro
citosol
Biološki proces GO:0009373 regulation of transcription, DNA-templated
Ćelijska diferencijacija
positive regulation of protein phosphorylation
GO:1903364 positive regulation of protein catabolic process
regulation of protein heterodimerization activity
positive regulation of cell migration
cellular response to tumor necrosis factor
negative regulation of apoptotic process
GO:1901227 negative regulation of transcription by RNA polymerase II
positive regulation of protein homodimerization activity
transcription, DNA-templated
positive regulation of cell differentiation
positive regulation of cell population proliferation
regulation of mitotic cell cycle
positive regulation of apoptotic process
negative regulation of cell population proliferation
GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II
positive regulation of NIK/NF-kappaB signaling
Izvori:Amigo / QuickGO
Ortolozi
VrsteČovjekMiš
Entrez
Ensembl
UniProt
RefSeq (mRNK)
NM_152943
NM_001165881
NM_001165882
NM_001165883
NM_001165884

NM_001165885
NM_001165886
NM_001165887
NM_003415

n/a

RefSeq (bjelančevina)
NP_001159353
NP_001159354
NP_001159355
NP_001159356
NP_001159357

NP_001159358
NP_001159359
NP_003406
NP_694422

n/a

Lokacija (UCSC)Chr 12: 133.18 – 133.21 Mbn/a
PubMed pretraga[2]n/a
Wikipodaci
Pogledaj/uredi – čovjek

Protein cinkovog prsta 268 je protein koji je kod ljudi kodiran genom ZNF268.[3][4]

Aminokiselinska sekvenca[uredi | uredi izvor]

Dužina polipeptidnog lanca je 94 aminokiseline, a molekulska težina 11 068 Da.[5]

Simboli
1020304050
MDVFVDFTWEEWQLLDPAQKCLYRSVMLENYSNLVSLGYQHTKPDIIFKL
EQGEELCMVQAQVPNQTCPNTVWKIDDLMDWHQENKDKLGSTAK

Reference[uredi | uredi izvor]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000090612 - Ensembl, maj 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ Abrink M, Aveskogh M, Hellman L (Mar 1995). "Isolation of cDNA clones for 42 different Kruppel-related zinc finger proteins expressed in the human monoblast cell line U-937". DNA Cell Biol. 14 (2): 125–36. doi:10.1089/dna.1995.14.125. PMID 7865130.
  4. ^ "Entrez Gene: ZNF268 zinc finger protein 268".
  5. ^ "UniProt, K7EMS6". Pristupljeno 8. 8. 2021.

Dopunska literatura[uredi | uredi izvor]