ZSCAN21

ZSCAN21
Identifikatori
Aliasi	ZSCAN21
Vanjski ID-jevi	OMIM: 601261 MGI: 99182 HomoloGene: 56530 GeneCards: ZSCAN21
Lokacija gena (čovjek)
Hrom.	Hromosom 7 (čovjek)
Kraj	100,065,040 bp
Lokacija gena (miš)
Hrom.	Hromosom 5 (miš)
Kraj	138,132,527 bp
Obrazac RNK ekspresije
	Više referentnih podataka o ekspresiji
Ontologija gena
Molekularna funkcija	• GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity; • GO:0000980 RNA polymerase II cis-regulatory region sequence-specific DNA binding; • vezivanje sa DNK; • GO:0001077, GO:0001212, GO:0001213, GO:0001211, GO:0001205 DNA-binding transcription activator activity, RNA polymerase II-specific; • GO:0001948, GO:0016582 vezivanje za proteine; • vezivanje iona metala; • nucleic acid binding; • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific;
Ćelijska komponenta	• jedro;
Biološki proces	• GO:0060469, GO:0009371 positive regulation of transcription, DNA-templated; • GO:0009373 regulation of transcription, DNA-templated; • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II; • transcription, DNA-templated; • transcription by RNA polymerase II;
	Izvori:Amigo / QuickGO
Ortolozi
	7589
	22697
	ENSG00000166529
	ENSMUSG00000037017
	Q9Y5A6
	Q07231
	NM_145914; NM_001362779; NM_001362780; NM_001362781
	NM_001044703; NM_001044704; NM_001044705; NM_011757
	NP_666019; NP_001349708; NP_001349709; NP_001349710
	NP_001038168; NP_001038169; NP_001038170; NP_035887
	Wikipodaci
Pogledaj/uredi – čovjek	Pogledaj/uredi – miš

Protein 21 cinkovog prsta sa domenom SCAN je protein koji je kod ljudi kodiran genom ZSCAN21.^[5]^[6]^[7]

Aminokiselinska sekvenca[uredi | uredi izvor]

Dužina polipeptidnog lanca je 473 aminokiseline, а molekulska težina 53.658 Da.^[8]

C: Cistein

D: Asparaginska kiselina

E: Glutaminska kiselina

F: Fenilalanin

G: Glicin

H: Histidin

I: Izoleucin

K: Lizin

L: Leucin

M: Metionin

N: Asparagin

P: Prolin

Q: Glutamin

R: Arginin

S: Serin

T: Treonin

V: Valin

W: Triptofan

Y: Tirozin

10	20	30	40	50
MMTKVLGMAP	VLGPRPPQEQ	VGPLMVKVEE	KEEKGKYLPS	LEMFRQRFRQ
FGYHDTPGPR	EALSQLRVLC	CEWLRPEIHT	KEQILELLVL	EQFLTILPQE
LQAWVQEHCP	ESAEEAVTLL	EDLERELDEP	GHQVSTPPNE	QKPVWEKISS
SGTAKESPSS	MQPQPLETSH	KYESWGPLYI	QESGEEQEFA	QDPRKVRDCR
LSTQHEESAD	EQKGSEAEGL	KGDIISVIIA	NKPEASLERQ	CVNLENEKGT
KPPLQEAGSK	KGRESVPTKP	TPGERRYICA	ECGKAFSNSS	NLTKHRRTHT
GEKPYVCTKC	GKAFSHSSNL	TLHYRTHLVD	RPYDCKCGKA	FGQSSDLLKH
QRMHTEEAPY	QCKDCGKAFS	GKGSLIRHYR	IHTGEKPYQC	NECGKSFSQH
AGLSSHQRLH	TGEKPYKCKE	CGKAFNHSSN	FNKHHRIHTG	EKPYWCHHCG
KTFCSKSNLS	KHQRVHTGEG	EAP

Reference[uredi | uredi izvor]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000166529 - Ensembl, maj 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000037017 - Ensembl, maj 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Thiesen HJ (Mar 1991). "Multiple genes encoding zinc finger domains are expressed in human T cells". New Biol. 2 (4): 363–374. PMID 2288909.
^ Huebner K, Druck T, Croce CM, Thiesen HJ (maj 1991). "Twenty-seven nonoverlapping zinc finger cDNAs from human T cells map to nine different chromosomes with apparent clustering". Am J Hum Genet. 48 (4): 726–740. PMC 1682948. PMID 2014798.
^ "Entrez Gene: ZSCAN21 zinc finger and SCAN domain containing 21".
^ "UniProt, Q9Y5A6" (jezik: engleski). Pristupljeno 26. 9. 2021.

Dopunska literatura[uredi | uredi izvor]

Carneiro FR; Silva TC; Alves AC; et al. (2006). "Spectroscopic characterization of the tumor antigen NY-REN-21 and identification of heterodimer formation with SCAND1". Biochem. Biophys. Res. Commun. 343 (1): 260–268. doi:10.1016/j.bbrc.2006.02.140. PMID 16540086.
Gerhard DS; Wagner L; Feingold EA; et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–2127. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Scherer SW; Cheung J; MacDonald JR; et al. (2003). "Human Chromosome 7: DNA Sequence and Biology". Science. 300 (5620): 767–772. doi:10.1126/science.1083423. PMC 2882961. PMID 12690205.
Strausberg RL; Feingold EA; Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–16903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Wiemann S; Weil B; Wellenreuther R; et al. (2001). "Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs". Genome Res. 11 (3): 422–435. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000166529 - Ensembl, maj 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000037017 - Ensembl, maj 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid2288909-5] Thiesen HJ (Mar 1991). "Multiple genes encoding zinc finger domains are expressed in human T cells". New Biol. 2 (4): 363–374. PMID 2288909.

[pmid2014798-6] Huebner K, Druck T, Croce CM, Thiesen HJ (maj 1991). "Twenty-seven nonoverlapping zinc finger cDNAs from human T cells map to nine different chromosomes with apparent clustering". Am J Hum Genet. 48 (4): 726–740. PMC 1682948. PMID 2014798.

[entrez-7] "Entrez Gene: ZSCAN21 zinc finger and SCAN domain containing 21".

[UniProt-8] "UniProt, Q9Y5A6" (jezik: engleski). Pristupljeno 26. 9. 2021.

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