ZNF436

ZNF436
Identifikatori
Aliasi	ZNF436
Vanjski ID-jevi	OMIM: 611703 MGI: 99192 HomoloGene: 40684 GeneCards: ZNF436
Lokacija gena (čovjek)
Hrom.	Hromosom 1 (čovjek)
Kraj	23,369,836 bp
Lokacija gena (miš)
Hrom.	Hromosom 4 (miš)
Kraj	136,021,253 bp
Ontologija gena
Molekularna funkcija	• GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity; • vezivanje sa DNK; • GO:0001948, GO:0016582 vezivanje za proteine; • vezivanje iona metala; • nucleic acid binding; • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific;
Ćelijska komponenta	• intracellular anatomical structure; • jedro; • nukleoplazma; • citosol;
Biološki proces	• GO:0009373 regulation of transcription, DNA-templated; • transcription, DNA-templated; • GO:0044324, GO:0003256, GO:1901213, GO:0046019, GO:0046020, GO:1900094, GO:0061216, GO:0060994, GO:1902064, GO:0003258, GO:0072212 regulation of transcription by RNA polymerase II;
	Izvori:Amigo / QuickGO
Ortolozi
	80818
	22704
	ENSG00000125945; ENSG00000283009
	ENSMUSG00000051351
	Q9C0F3
	Q8BPP0
	NM_001077195; NM_030634; NM_001370652
	NM_009557; NM_001356308; NM_001370651
	NP_001070663; NP_085137; NP_001357581
	NP_033583; NP_001343237; NP_001357580
	Wikipodaci
Pogledaj/uredi – čovjek	Pogledaj/uredi – miš

Protein 436 cinkovog prsta jest protein koji je kod ljudi kodiran genom ZNF436 sa hromosoma 1.^[5]^[6]

Aminokiselinska sekvenca[uredi | uredi izvor]

Dužina polipeptidnog lanca je 470 aminokiselina, a molekulska težina 54.277 Da.^[7]

C: Cistein

D: Asparaginska kiselina

E: Glutaminska kiselina

F: Fenilalanin

G: Glicin

H: Histidin

I: Izoleucin

K: Lizin

L: Leucin

M: Metionin

N: Asparagin

P: Prolin

Q: Glutamin

R: Arginin

S: Serin

T: Treonin

V: Valin

W: Triptofan

Y: Tirozin

10	20	30	40	50
MAATLLMAGS	QAPVTFEDMA	MYLTREEWRP	LDAAQRDLYR	DVMQENYGNV
VSLDFEIRSE	NEVNPKQEIS	EDVQFGTTSE	RPAENAEENP	ESEEGFESGD
RSERQWGDLT	AEEWVSYPLQ	PVTDLLVHKE	VHTGIRYHIC	SHCGKAFSQI
SDLNRHQKTH	TGDRPYKCYE	CGKGFSRSSH	LIQHQRTHTG	ERPYDCNECG
KSFGRSSHLI	QHQTIHTGEK	PHKCNECGKS	FCRLSHLIQH	QRTHSGEKPY
ECEECGKSFS	RSSHLAQHQR	THTGEKPYEC	NECGRGFSER	SDLIKHYRVH
TGERPYKCDE	CGKNFSQNSD	LVRHRRAHTG	EKPYHCNECG	ENFSRISHLV
QHQRTHTGEK	PYECNACGKS	FSRSSHLITH	QKIHTGEKPY	ECNECWRSFG
ERSDLIKHQR	THTGEKPYEC	VQCGKGFTQS	SNLITHQRVH	TGEKPYECTE
CEKSFSRSSA	LIKHKRVHTD

Također pogledajte[uredi | uredi izvor]

ZNF692

Reference[uredi | uredi izvor]

^ ^a ^b ^c ENSG00000283009 GRCh38: Ensembl release 89: ENSG00000125945, ENSG00000283009 - Ensembl, maj 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000051351 - Ensembl, maj 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Nagase T, Kikuno R, Hattori A, Kondo Y, Okumura K, Ohara O (Feb 2001). "Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 7 (6): 347–55. doi:10.1093/dnares/7.6.347. PMID 11214970.
^ "Entrez Gene: ZNF436 zinc finger protein 436".
^ "UniProt, Q9C0F3" (jezik: eng.). Pristupljeno 26. 11. 2021.CS1 održavanje: nepoznati jezik (link)

Dopunska literatura[uredi | uredi izvor]

Li Y, Du X, Li F, et al. (2007). "A novel zinc-finger protein ZNF436 suppresses transcriptional activities of AP-1 and SRE". Mol. Biol. Rep. 33 (4): 287–94. doi:10.1007/s11033-006-9019-5. PMID 17089209. S2CID 13591444.
Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. Bibcode:2006Natur.441..315G. doi:10.1038/nature04727. PMID 16710414.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Bray P, Lichter P, Thiesen HJ, et al. (1991). "Characterization and mapping of human genes encoding zinc finger proteins". Proc. Natl. Acad. Sci. U.S.A. 88 (21): 9563–7. Bibcode:1991PNAS...88.9563B. doi:10.1073/pnas.88.21.9563. PMC 52758. PMID 1946370.
Lichter P, Bray P, Ried T, et al. (1992). "Clustering of C2-H2 zinc finger motif sequences within telomeric and fragile site regions of human chromosomes". Genomics. 13 (4): 999–1007. doi:10.1016/0888-7543(92)90013-I. PMID 1505991.

[refGRCh38Ensembl-1] ENSG00000283009 GRCh38: Ensembl release 89: ENSG00000125945, ENSG00000283009 - Ensembl, maj 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000051351 - Ensembl, maj 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11214970-5] Nagase T, Kikuno R, Hattori A, Kondo Y, Okumura K, Ohara O (Feb 2001). "Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 7 (6): 347–55. doi:10.1093/dnares/7.6.347. PMID 11214970.

[entrez-6] "Entrez Gene: ZNF436 zinc finger protein 436".

[UniProt-7] "UniProt, Q9C0F3" (jezik: eng.). Pristupljeno 26. 11. 2021.CS1 održavanje: nepoznati jezik (link)

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