TTC37

TTC37
Identifikatori
Aliasi	TTC37
Vanjski ID-jevi	OMIM: 614589 MGI: 2679923 HomoloGene: 40966 GeneCards: TTC37
Lokacija gena (čovjek)
Hrom.	Hromosom 5 (čovjek)
Kraj	95,554,977 bp
Lokacija gena (miš)
Hrom.	Hromosom 13 (miš)
Kraj	76,338,435 bp
Ontologija gena
Molekularna funkcija	• GO:0001948, GO:0016582 vezivanje za proteine;
Ćelijska komponenta	• Ski complex; • nukleoplazma; • jedro; • citoplazma; • citosol;
Biološki proces	• exonucleolytic catabolism of deadenylated mRNA; • RNA catabolic process;
	Izvori:Amigo / QuickGO
Ortolozi
	9652
	218343
	ENSG00000198677
	ENSMUSG00000033991
	Q6PGP7
	F8VPK0
	NM_014639
	NM_001081352
	NP_055454
	NP_001074821
	Wikipodaci
Pogledaj/uredi – čovjek	Pogledaj/uredi – miš

Tetratrikopeptidni ponavljajući domen 37 (TTC37) jest protein koji je kod ljudi kodiran genom sa hromosoma 5.^[5]^[6]

Aminokiselinska sekvenca[uredi | uredi izvor]

Dužina polipeptidnog lanca je 1.564 aminokiseline, a molekulska težina 175.486 Da.^[6]

C: Cistein

D: Asparaginska kiselina

E: Glutaminska kiselina

F: Fenilalanin

G: Glicin

H: Histidin

I: Izoleucin

K: Lizin

L: Leucin

M: Metionin

N: Asparagin

P: Prolin

Q: Glutamin

R: Arginin

S: Serin

T: Treonin

V: Valin

W: Triptofan

Y: Tirozin

10	20	30	40	50
MSSKEVKTAL	KSARDAIRNK	EYKEALKHCK	TVLKQEKNNY	NAWVFIGVAA
AELEQPDQAQ	SAYKKAAELE	PDQLLAWQGL	ANLYEKYNHI	NAKDDLPGVY
QKLLDLYESV	DKQKWCDVCK	KLVDLYYQEK	KHLEVARTWH	KLIKTRQEQG
AENEELHQLW	RKLTQFLAES	TEDQNNETQQ	LLFTAFENAL	GLSDKIPSED
HQVLYRHFIQ	SLSKFPHESA	RLKKACEGMI	NIYPTVQYPL	EVLCLHLIES
GNLTDEGQQY	CCRLVEMDSK	SGPGLIGLGI	KALQDKKYED	AVRNLTEGLK
ESPVCTSGWY	HLAEAQVKMH	RPKEAVLSCS	QALKIVDNLG	ASGNSLYQRN
LCLHLKAEAL	IKLSDYDSSE	EAIRTLDQIS	DADNIPGLLV	LKSLAYRNKG
SFDEAAKIME	DLLSSYPDLA	EVHALEALIH	FTKKDYLQAE	KCFQRALEKD
TEVAEYHYQL	GLTYWFMGEE	TRKDKTKALT	HFLKAARLDT	YMGKVFCYLG
HYYRDVVGDK	NRARGCYRKA	FELDDTDAES	GAAAVDLSVE	LEDMEMALAI
LTTVTQKASA	GTAKWAWLRR	GLYYLKAGQH	SQAVADLQAA	LRADPKDFNC
WESLGEAYLS	RGGYTTALKS	FTKASELNPE	SIYSVFKVAA	IQQILGKYKE
AVAQYQMIIK	KKEDYVPALK	GLGECHLMMA	KAALVDYLDG	KAVDYIEKAL
EYFTCALQHR	ADVSCLWKLA	GDACTCLYAV	APSKVNVHVL	GVLLGQKEGK
QVLKKNELLH	LGGRCYGRAL	KLMSTSNTWC	DLGINYYRQA	QHLAETGSNM
NDLKELLEKS	LHCLKKAVRL	DSNNHLYWNA	LGVVACYSGI	GNYALAQHCF
IKSIQSEQIN	AVAWTNLGVL	YLTNENIEQA	HEAFKMAQSL	DPSYLMCWIG
QALIAEAVGS	YDTMDLFRHT	TELNMHTEGA	LGYAYWVCTT	LQDKSNRETE
LYQYNILQMN	AIPAAQVILN	KYVERIQNYA	PAFTMLGYLN	EHLQLKKEAA
NAYQRAILLL	QTAEDQDTYN	VAIRNYGRLL	CSTGEYDKAI	QAFKSTPLEV
LEDIIGFALA	LFMKGLYKES	SKAYERALSI	VESEQDKAHI	LTALAITEYK
QGKTDVAKTL	LFKCSILKEP	TTESLQALCA	LGLAMQDATL	SKAALNELLK
HIKHKDSNYQ	RCLLTSAIYA	LQGRSVAVQK	QISKAVHSNP	GDPALWSLLS
RVVAQYAQRN	AKGGVVAGNV	AHILDSNHGK	KALLYTAVNQ	LAMGSSSAED
EKNTALKTIQ	KAALLSPGDP	AIWAGLMAAC	HADDKLALVN	NTQPKRIDLY
LALLSAVSAS	IKDEKFFENY	NQSLEKWSLS	QAVTGLIDTG	RISEAETLCT
KNLKSNPDQP	AVILLLRQVQ	CKPLLESQKP	LPDAVLEELQ	KTVMSNSTSV
PAWQWLAHVY	QSQGMMRAAE	MCYRKSLQLA	SQRGSWSGKL	SSLLRLALLA
LKVCMANISN	DHWPSLVQEA	TTEALKLCFC	PLAVLLQALL	QFKRKMGARE
TRRLLERVVY	QPGYPKSIAS	TARWYLLRHL	YAKDDYELID	VLVNNAKTHG
DTRALELNQR	LSSQ

Funkcija[uredi | uredi izvor]

Uključen je u takav biološki proces kao što je acetilacija.

Lokaliziran je u citoplazmi ijezdru.

Reference[uredi | uredi izvor]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000198677 - Ensembl, maj 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000033991 - Ensembl, maj 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "HUGO Gene Nomenclature Commitee, HGNC:23639" (jezik: engleski). Arhivirano s originala, 16. 9. 2017. Pristupljeno 18. 9. 2017.
^ ^a ^b "UniProt, Q6PGP7" (jezik: engleski). Pristupljeno 18. 9. 2017.

Dopunska literatura[uredi | uredi izvor]

NIH (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14: 2121–2127. PubMed doi:10.1101/gr.2596504

Vanjski linkovi[uredi | uredi izvor]

Portal Biologija

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000198677 - Ensembl, maj 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000033991 - Ensembl, maj 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[HGNC-5] "HUGO Gene Nomenclature Commitee, HGNC:23639" (jezik: engleski). Arhivirano s originala, 16. 9. 2017. Pristupljeno 18. 9. 2017.

[UniProt-6] "UniProt, Q6PGP7" (jezik: engleski). Pristupljeno 18. 9. 2017.

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