Datoteka:Steroidogenesis.png

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Sažetak

Opis
English: Enzymes, their cellular location, substrates and products in human steroidogenesis.

Shown also is the major classes of steroid hormones: progestagens, mineralocorticoids, glucocorticoids, androgens and estrogens. However, they partly overlap, e.g. mineralocorticoids and glucocorticoids.

White circles indicate changes in molecular structure compared with precursors. For more information on interpretation of molecular structures, see Wikipedia:structural formula.

HSD: Hydroxysteroid dehydrogenase

References:

There is no appreciable conversion of corticosterone to cortisol in the adrenal cortex as 21-OH steroids are poor substrates for 17-alpha hydroxylase.
Polski: Enzymy biorące udział w steroidogenezie.

Uwagi: W miejscu gdzie stereochemia nie jest wyświetlana, jest taka sama jak dla Cholesterol lub w pokazanej powyżej grupie.

HSD: Dehydrogenaza hydroksysteroidu
Datum
Izvor Self-made using bkchem and inkscape
Autor

David Richfield (User:Slashme) and Mikael Häggström. Derived from previous version by Hoffmeier and Settersr.

In external use, this diagram may be cited as:

Ostale verzije

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Evolution

A short flashback of some milestones the evolution of the picture, demonstrating the power of free licensing where anybody can contribute to making things better.

1. (March 2007) Previous image by Stannered.
4. (August 2008) Vector (.svg) version by Slashme.
2. (July 2007) Molecular structures added by Hoffmeier and Settersr.
5. (March 2009) Colouring and further organization by Mikael Häggström.
3. (November 2007) Organization and addition of enzymes by Mikael Häggström.
File:Steroidogenesis.svg is a vector version of this file. It should be used in place of this PNG file when not inferior.
File:Steroidogenesis.png → File:Steroidogenesis.svg
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Historija datoteke

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(najnovije | najstarije) Pogledaj (novije 10 | ) (10 | 20 | 50 | 100 | 250 | 500)
Datum/vrijemeSmanjeni pregledDimenzijeKorisnikKomentar
trenutno17:22, 13 mart 2013Smanjeni pregled verzije na dan 17:22, 13 mart 20132.075 × 1.842 (940 KB)SlashmeRemoved link from corticosterone to cortisol via CYP17A1, which is incorrect (according to http://www.genome.jp/kegg-bin/show_pathway?ko00140+C02140 )
18:15, 9 juli 2012Smanjeni pregled verzije na dan 18:15, 9 juli 20122.075 × 1.842 (932 KB)Mikael HäggströmAddition and correction of stereochemistries at positions 11 and 17.
06:24, 9 juli 2012Smanjeni pregled verzije na dan 06:24, 9 juli 20122.075 × 1.842 (928 KB)Mikael HäggströmAdded stereochemistries, removed redundant white circle at cortisol, renamed 21-alpha hydroxylase to simply 21-hydroxylase.
07:17, 13 decembar 2011Smanjeni pregled verzije na dan 07:17, 13 decembar 20111.314 × 1.166 (530 KB)SlashmeAlign some text and arrows for neatness' sake.
07:03, 13 decembar 2011Smanjeni pregled verzije na dan 07:03, 13 decembar 20111.314 × 1.166 (530 KB)SlashmeFixed reaction scheme: corticosterone doesn't go to cortisol! Karl and Lindie, why didn't you fix it when you first found out? Tsk tsk.
14:56, 8 maj 2010Smanjeni pregled verzije na dan 14:56, 8 maj 20101.314 × 1.162 (510 KB)Mikael Häggströmminor renaming of 3-beta-HSD
11:28, 18 april 2010Smanjeni pregled verzije na dan 11:28, 18 april 20101.314 × 1.162 (510 KB)Mikael HäggströmMoved pregnenolone out of molecular structure
10:54, 1 novembar 2009Smanjeni pregled verzije na dan 10:54, 1 novembar 20091.003 × 883 (253 KB)Mikael Häggström"Bunny-jumped", since the change earlier probably was too small to make it want to really update, but that misplaced 6 was important.
10:53, 1 novembar 2009Smanjeni pregled verzije na dan 10:53, 1 novembar 2009621 × 767 (428 KB)Mikael Häggströmsee above
10:49, 1 novembar 2009Smanjeni pregled verzije na dan 10:49, 1 novembar 20091.003 × 883 (253 KB)Mikael Häggströmmoved misplaced nr 6
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