Izvorni kôd stranice UPK2

{{Infokutija gen}}
'''Uroplakin-2''' je [[protein]] koji je kod [[ljudi]] [[kodon|kodiran]] [[gen]]gom '''UPK2'''.<ref name="pmid9515818">{{cite journal | vauthors = Wu RL, Osman I, Wu XR, Lu ML, Zhang ZF, Liang FX, Hamza R, Scher H, Cordon-Cardo C, Sun TT | title = Uroplakin II gene is expressed in transitional cell carcinoma but not in bilharzial bladder squamous cell carcinoma: alternative pathways of bladder epithelial differentiation and tumor formation | journal = Cancer Res | volume = 58 | issue = 6 | pages = 1291–7 | pmid = 9515818| year = 1998 }}</ref><ref name="pmid9846985">{{cite journal | vauthors = Lobban ED, Smith BA, Hall GD, Harnden P, Roberts P, Selby PJ, Trejdosiewicz LK, Southgate J | title = Uroplakin gene expression by normal and neoplastic human urothelium | journal = Am J Pathol | volume = 153 | issue = 6 | pages = 1957–67 |date=Dec 1998 | pmid = 9846985 | pmc = 1866332 | doi =10.1016/S0002-9440(10)65709-4  }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: UPK2 uroplakin 2| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7379}}</ref>
;Aminokiselinska sekvenca
Dužina [[polipeptid]]nog lanca je 184 [[aminokiselina]], а [[molekularna masa|molekulska težina]]  19.438 [[dalton (jedinica)|Da]].<ref name="UniProt">{{cite web|url=http://www.uniprot.org/uniprot/O00526#sequences |title=UniProt, O00526|access-date=28. 8. 2021}}</ref>.
{{legenda aminokiselina}}

<table  style="font-family:monospace;">
<tr style="text-align:right;"><th>10</th><th></th><th>20</th><th></th><th>30</th><th></th><th>40</th><th></th><th>50</th></tr>
<tr style="background-color: #eee;"><td>MAPLLPIRTL</td><td style="background-color: #f9f9f9;"></td><td>PLILILLALL</td><td style="background-color: #f9f9f9;"></td><td>SPGAADFNIS</td><td style="background-color: #f9f9f9;"></td><td>SLSGLLSPAL</td><td style="background-color: #f9f9f9;"></td><td>TESLLVALPP</td></tr>
<tr style="background-color: #eee;"><td>CHLTGGNATL</td><td style="background-color: #f9f9f9;"></td><td>MVRRANDSKV</td><td style="background-color: #f9f9f9;"></td><td>VTSSFVVPPC</td><td style="background-color: #f9f9f9;"></td><td>RGRRELVSVV</td><td style="background-color: #f9f9f9;"></td><td>DSGAGFTVTR</td></tr>
<tr style="background-color: #eee;"><td>LSAYQVTNLV</td><td style="background-color: #f9f9f9;"></td><td>PGTKFYISYL</td><td style="background-color: #f9f9f9;"></td><td>VKKGTATESS</td><td style="background-color: #f9f9f9;"></td><td>REIPMSTLPR</td><td style="background-color: #f9f9f9;"></td><td>RNMESIGLGM</td></tr>
<tr style="background-color: #eee;"><td>ARTGGMVVIT</td><td style="background-color: #f9f9f9;"></td><td>VLLSVAMFLL</td><td style="background-color: #f9f9f9;"></td><td>VLGFIIALAL</td><td style="background-color: #f9f9f9;"></td><td>GSRK</td></tr>
</table>

==Reference==
{{reflist}}

==Dopunska literatura==
{{refbegin | 2}}
*{{cite journal  | vauthors=Lin JH, Wu XR, Kreibich G, Sun TT |title=Precursor sequence, processing, and urothelium-specific expression of a major 15-kDa protein subunit of asymmetric unit membrane |journal=J. Biol. Chem. |volume=269 |issue= 3 |pages= 1775–84 |year= 1994 |pmid= 7507484 }}
*{{cite journal   |vauthors=Wu XR, Lin JH, Walz T, etal |title=Mammalian uroplakins. A group of highly conserved urothelial differentiation-related membrane proteins |journal=J. Biol. Chem. |volume=269 |issue= 18 |pages= 13716–24 |year= 1994 |pmid= 8175808 }}
*{{cite journal   |vauthors=Yuasa T, Yoshiki T, Isono T, etal |title=Expression of transitional cell-specific genes, uroplakin Ia and II, in bladder cancer: detection of circulating cancer cells in the peripheral blood of metastatic patients |journal=Int. J. Urol. |volume=6 |issue= 6 |pages= 286–92 |year= 1999 |pmid= 10404304 |doi=10.1046/j.1442-2042.1999.00064.x  |s2cid=43597402 }}
*{{cite journal   |vauthors=Li SM, Zhang ZT, Chan S, etal |title=Detection of circulating uroplakin-positive cells in patients with transitional cell carcinoma of the bladder |journal=J. Urol. |volume=162 |issue= 3 Pt 1 |pages= 931–5 |year= 1999 |pmid= 10458411 |doi=10.1097/00005392-199909010-00093  }}
*{{cite journal  | vauthors=Ogawa K, Johansson SL, Cohen SM |title=Immunohistochemical analysis of uroplakins, urothelial specific proteins, in ovarian Brenner tumors, normal tissues, and benign and neoplastic lesions of the female genital tract |journal=Am. J. Pathol. |volume=155 |issue= 4 |pages= 1047–50 |year= 1999 |pmid= 10514386 |doi=  10.1016/S0002-9440(10)65206-6| pmc=1867018  }}
*{{cite journal  | vauthors=Tu L, Sun TT, Kreibich G |title=Specific heterodimer formation is a prerequisite for uroplakins to exit from the endoplasmic reticulum |journal=Mol. Biol. Cell |volume=13 |issue= 12 |pages= 4221–30 |year= 2003 |pmid= 12475947 |doi= 10.1091/mbc.E02-04-0211  | pmc=138628 }}
*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899  | pmc=139241 }}
*{{cite journal   |vauthors=Hirata H, Hisatomi H, Kawakita M, etal |title=Genetic detection for hematogenous micrometastasis in patients with various types of malignant tumors using Uroplakin II derived primers in polymerase chain reaction |journal=Oncol. Rep. |volume=10 |issue= 4 |pages= 963–6 |year= 2004 |pmid= 12792753 |doi=  10.3892/or.10.4.963}}
*{{cite journal   |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504  | pmc=528928 }}
*{{cite journal   |vauthors=Chen F, Zeng F, Tong Q, etal |title=Cloning of human uroplakin II gene from Chinese transitional cell carcinoma of bladder and construction of its eukaryotic expression vector |journal=J. Huazhong Univ. Sci. Technol. Med. Sci. |volume=25 |issue= 2 |pages= 188–90, 211 |year= 2006 |pmid= 16116969 |doi=10.1007/BF02873573  |s2cid=7772680 |url=https://www.semanticscholar.org/paper/1e2cfeb410e9f193832e5d3f1363ed025425066f }}
*{{cite journal   |vauthors=Jenkins D, Bitner-Glindzicz M, Malcolm S, etal |title=Mutation analyses of Uroplakin II in children with renal tract malformations |journal=Nephrol. Dial. Transplant. |volume=21 |issue= 12 |pages= 3415–21 |year= 2007 |pmid= 17012268 |doi= 10.1093/ndt/gfl465 |doi-access= free }}
{{refend}}

[[Kategorija:Uroplakini]]
[[Kategorija:Geni na hromosomu 11]]
[[Kategorija:Ljudski proteini]]
[[Kategorija:Proteomika]]