RPS6KA6

RPS6KA6
Identifikatori
Aliasi	RPS6KA6
Vanjski ID-jevi	OMIM: 300303 MGI: 1914321 HomoloGene: 22816 GeneCards: RPS6KA6
Lokacija gena (miš)
Hrom.	Hromosom X (miš)
Kraj	110,447,656 bp
Ontologija gena
Molekularna funkcija	• aktivnost sa transferazom; • nucleotide binding; • vezivanje iona metala; • ATP binding; • magnesium ion binding; • protein serine/threonine kinase activity; • kinase activity; • protein kinase activity; • ribosomal protein S6 kinase activity;
Ćelijska komponenta	• citoplazma; • Jedarce; • mitohondrija; • jedro; • citosol; • fibrillar center; • nukleoplazma;
Biološki proces	• GO:0007243 intracellular signal transduction; • Fosforilacija; • protein phosphorylation; • negative regulation of embryonic development; • central nervous system development; • negative regulation of mesoderm development; • negative regulation of ERK1 and ERK2 cascade; • GO:0072468 Transdukcija signala; • DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator;
	Izvori:Amigo / QuickGO
Ortolozi
	27330
	67071
	n/a
	ENSMUSG00000025665
	Q9UK32
	Q7TPS0
	NM_014496; NM_001330512
	NM_025949; NM_001374707; NM_001398774
	NP_001317441; NP_055311
	NP_080225; NP_001361636; NP_001385703
	Wikipodaci
Pogledaj/uredi – čovjek	Pogledaj/uredi – miš

Polipeptid 6 ribosomne protein S6-kinaze, 90kDa je protein koji je kod ljudi kodiran genom RPS6KA6.^[4]

Ovaj gen kodira člana porodice ribosomskih S6-kinaza, serin-treonin proteinske kinaze koje reguliraju faktori rasta. Kodirani protein može se razlikovati od ostalih članova ove porodice, ali, budući da studije sugeriraju da ne ovisi o faktoru rasta i možda ne sudjeluje u istim signalnim putovima. [premaRefSeq, januar 2010.].

Reference[uredi | uredi izvor]

^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000025665 - Ensembl, maj 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: Ribosomal protein S6 kinase, 90kDa, polypeptide 6". Pristupljeno 15. 1. 2013.

[refGRCm38Ensembl-1] GRCm38: Ensembl release 89: ENSMUSG00000025665 - Ensembl, maj 2017

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[3] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-4] "Entrez Gene: Ribosomal protein S6 kinase, 90kDa, polypeptide 6". Pristupljeno 15. 1. 2013.

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