RPS4Y1

RPS4Y1
Dostupne strukture PDB Pretraga ortologa: PDBe RCSB Spisak PDB ID kodova 5AJ0, 5FLX, 4D61, 4D5L, 4UJD, 4UJE, 4UJC
Identifikatori
Aliasi	RPS4Y1
Vanjski ID-jevi	OMIM: 470000 MGI: 98158 HomoloGene: 133576 GeneCards: RPS4Y1
Lokacija gena (miš) Hrom. Hromosom X (miš) Bend X D|X 45.2 cM Početak 101,228,547 bp Kraj 101,233,000 bp
Obrazac RNK ekspresije Više referentnih podataka o ekspresiji
Ontologija gena Molekularna funkcija • rRNA binding • structural constituent of ribosome • vezivanje sa RNK Ćelijska komponenta • ribozom • polysome • citosol • jedro • membrana • intracellular anatomical structure • nukleoplazma • cytosolic small ribosomal subunit Biološki proces • SRP-dependent cotranslational protein targeting to membrane • viral transcription • multicellular organism development • Nonsens-posredovano propadanje iRNK • translational initiation • Biosinteza bjelančevina • rRNA processing Izvori:Amigo / QuickGO
Ortolozi
Vrste	Čovjek	Miš
Entrez	6192	20102
Ensembl	n/a	ENSMUSG00000031320
UniProt	P22090	P62702
RefSeq (mRNK)	NM_001008	NM_009094
RefSeq (bjelančevina)	NP_000999	NP_033120
Lokacija (UCSC)	n/a	Chr X: 101.23 – 101.23 Mb
PubMed pretraga
Wikipodaci
Pogledaj/uredi – čovjek Pogledaj/uredi – miš

40S ribosomski protein S4, Y izoforma 1 je protein koji je kod ljudi kodiran genom RPS4Y1.

Citoplazmatski ribosomi, organele koje kataliziraju sintezu proteina, sastoje se od male 40S i velike 60S podjedinice. Zajedno se ove podjedinice sastoje od četiti tipa molekula RNK i približno 80 strukturno različitih proteina. Ovaj gen kodira ribosomski protein S4, komponentu podjedinice 40S. Ribosomski protein S4 jedini je ribosomski protein za koji je poznato da ga kodira više od jednog gena. To su ovaj gen, RPS4Y2 i ribosomski protein S4, X-vezani (RPS4X).Tri izoforme kodirane ovim genima nisu identične, ali izgleda da su funkcijski ekvivalenti. Ribosomski protein S4 pripada porodici S4E ribosomskih proteina. Sugerira se da haploinsuficijencija gena ribosomskog proteina S4 ima ulogu u Turnerovom sindromu; ova hipoteza je, međutim, kontroverzna.

Također pogledajte

• Domen proteina S4

Dopunska literatura

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