Šablon:UEFA Evropska liga 2018/19 - 1/8
Prve utakmice su odigrane 7. marta, a uzvratne 14. marta 2019.
| Tim 1 | Rez. | Tim 2 | Prva utakmica | Druga utakmica |
|---|---|---|---|---|
Chelsea 
|
8–0 |  Dinamo Kijev
|
3–0 | 5–0 |
Eintracht Frankfurt 
|
1–0 |  Inter Milano
|
0–0 | 1–0 |
Dinamo Zagreb 
|
1–3 |  Benfica
|
1–0 | 0–3 (a.e.t.) |
| Napoli
|
4–3 |  Red Bull Salzburg
|
3–0 | 1–3 |
Valencia 
|
3–2 |  Krasnodar
|
2–1 | 1–1 |
| Sevilla
|
5–6 |  Slavia Prag
|
2–2 | 3–4 (a.e.t.) |
Rennes 
|
3–4 | Arsenal
|
3–1 | 0–3 |
| Zenit Sankt Peterburg
|
2–5 | Villarreal
|
1–3 | 1–2 |