CAMTA1

CAMTA1
Dostupne strukture PDB Pretraga ortologa: PDBe RCSB Spisak PDB ID kodova 2CXK
Identifikatori
Aliasi	CAMTA1
Vanjski ID-jevi	OMIM: 611501 MGI: 2140230 HomoloGene: 18942 GeneCards: CAMTA1
Lokacija gena (miš) Hrom. Hromosom 4 (miš) Bend 4|4 E2 Početak 150,917,322 bp Kraj 151,861,876 bp
Obrazac RNK ekspresije Više referentnih podataka o ekspresiji
Ontologija gena Molekularna funkcija • sequence-specific DNA binding • vezivanje sa DNK • GO:0001077, GO:0001212, GO:0001213, GO:0001211, GO:0001205 DNA-binding transcription activator activity, RNA polymerase II-specific • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific Ćelijska komponenta • jedro • Jedarce • citoplazma • citosol Biološki proces • GO:0009373 regulation of transcription, DNA-templated • neuromuscular process controlling balance • transcription, DNA-templated • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II • transcription by RNA polymerase II • positive regulation of protein dephosphorylation • positive regulation of calcineurin-NFAT signaling cascade Izvori:Amigo / QuickGO
Ortolozi
Vrste	Čovjek	Miš
Entrez	23261	100072
Ensembl	ENSG00000171735	ENSMUSG00000014592
UniProt	Q9Y6Y1	A2A891
RefSeq (mRNK)	NM_001195563 NM_001242701 NM_015215	NM_001081557 NM_001166021 NM_001195565
RefSeq (bjelančevina)	NP_001182492 NP_001229630 NP_056030 NP_001336537 NP_001336538 NP_001336539 NP_001336541 NP_001336542 NP_001336543 NP_001336544 NP_001336545 NP_001336546 NP_001336547 NP_001336548 NP_001336549 NP_001336550 NP_001336551 NP_001336552 NP_001336553 NP_001336554 NP_001336555 NP_001336556	NP_001075026 NP_001182494
Lokacija (UCSC)	n/a	Chr 4: 150.92 – 151.86 Mb
PubMed pretraga
Wikipodaci
Pogledaj/uredi – čovjek Pogledaj/uredi – miš

Kalmodulin-vezujući transkripcijski aktivator 1 jest protein koji je kod ljudi kodiran genom CAMTA1 sa hromosoma 1.

Aminokiselinska sekvenca

Dužina polipeptidnog lanca je 1.673 aminokiselina, a molekulska težina 183.672 Da.

• C: Cistein
• D: Asparaginska kiselina
• E: Glutaminska kiselina
• F: Fenilalanin
• G: Glicin
• H: Histidin
• I: Izoleucin
• K: Lizin
• L: Leucin
• M: Metionin
• N: Asparagin
• P: Prolin
• Q: Glutamin
• R: Arginin
• S: Serin
• T: Treonin
• V: Valin
• W: Triptofan
• Y: Tirozin

10		20		30		40		50
MWRAEGKWLP		KTSRKSVSQS		VFCGTSTYCV		LNTVPPIEDD		HGNSNSSHVK
IFLPKKLLEC		LPKCSSLPKE		RHRWNTNEEI		AAYLITFEKH		EEWLTTSPKT
RPQNGSMILY		NRKKVKYRKD		GYCWKKRKDG		KTTREDHMKL		KVQGVECLYG
CYVHSSIIPT		FHRRCYWLLQ		NPDIVLVHYL		NVPAIEDCGK		PCGPILCSIN
TDKKEWAKWT		KEELIGQLKP		MFHGIKWTCS		NGNSSSGFSV		EQLVQQILDS
HQTKPQPRTH		NCLCTGSLGA		GGSVHHKCNS		AKHRIISPKV		EPRTGGYGSH
SEVQHNDVSE		GKHEHSHSKG		SSREKRNGKV		AKPVLLHQSS		TEVSSTNQVE
VPDTTQSSPV		SISSGLNSDP		DMVDSPVVTG		VSGMAVASVM		GSLSQSATVF
MSEVTNEAVY		TMSPTAGPNH		HLLSPDASQG		LVLAVSSDGH		KFAFPTTGSS
ESLSMLPTNV		SEELVLSTTL		DGGRKIPETT		MNFDPDCFLN		NPKQGQTYGG
GGLKAEMVSS		NIRHSPPGER		SFSFTTVLTK		EIKTEDTSFE		QQMAKEAYSS
SAAAVAASSL		TLTAGSSLLP		SGGGLSPSTT		LEQMDFSAID		SNKDYTSSFS
QTGHSPHIHQ		TPSPSFFLQD		ASKPLPVEQN		THSSLSDSGG		TFVMPTVKTE
ASSQTSSCSG		HVETRIESTS		SLHLMQFQAN		FQAMTAEGEV		TMETSQAAEG
SEVLLKSGEL		QACSSEHYLQ		PETNGVIRSA		GGVPILPGNV		VQGLYPVAQP
SLGNASNMEL		SLDHFDISFS		NQFSDLINDF		ISVEGGSSTI		YGHQLVSGDS
TALSQSEDGA		RAPFTQAEMC		LPCCSPQQGS		LQLSSSEGGA		STMAYMHVAE
VVSAASAQGT		LGMLQQSGRV		FMVTDYSPEW		SYPEGGVKVL		ITGPWQEASN
NYSCLFDQIS		VPASLIQPGV		LRCYCPAHDT		GLVTLQVAFN		NQIISNSVVF
EYKARALPTL		PSSQHDWLSL		DDNQFRMSIL		ERLEQMERRM		AEMTGSQQHK
QASGGGSSGG		GSGSGNGGSQ		AQCASGTGAL		GSCFESRVVV		VCEKMMSRAC
WAKSKHLIHS		KTFRGMTLLH		LAAAQGYATL		IQTLIKWRTK		HADSIDLELE
VDPLNVDHFS		CTPLMWACAL		GHLEAAVVLY		KWDRRAISIP		DSLGRLPLGI
ARSRGHVKLA		ECLEHLQRDE		QAQLGQNPRI		HCPASEEPST		ESWMAQWHSE
AISSPEIPKG		VTVIASTNPE		LRRPRSEPSN		YYSSESHKDY		PAPKKHKLNP
EYFQTRQEKL		LPTALSLEEP		NIRKQSPSSK		QSVPETLSPS		EGVRDFSREL
SPPTPETAAF		QASGSQPVGK		WNSKDLYIGV		STVQVTGNPK		GTSVGKEAAP
SQVRPREPMS		VLMMANREVV		NTELGSYRDS		AENEECGQPM		DDIQVNMMTL
AEHIIEATPD		RIKQENFVPM		ESSGLERTDP		ATISSTMSWL		ASYLADADCL
PSAAQIRSAY		NEPLTPSSNT		SLSPVGSPVS		EIAFEKPNLP		SAADWSEFLS
ASTSEKVENE		FAQLTLSDHE		QRELYEAARL		VQTAFRKYKG		RPLREQQEVA
AAVIQRCYRK		YKQYALYKKM		TQAAILIQSK		FRSYYEQKKF		QQSRRAAVLI
QKYYRSYKKC		GKRRQARRTA		VIVQQKLRSS		LLTKKQDQAA		RKIMRFLRRC
RHSPLVDHRL		YKRSERIEKG		QGT

Dopunska literatura

• Katoh M, Katoh M (2004). "Identification and characterization of FLJ10737 and CAMTA1 genes on the commonly deleted region of neuroblastoma at human chromosome 1p36.31-p36.23". International Journal of Oncology. 23 (4): 1219–24. doi:10.3892/ijo.23.4.1219. PMID 12964007.
• Nakatani K, Nishioka J, Itakura T, et al. (2004). "Cell cycle-dependent transcriptional regulation of calmodulin-binding transcription activator 1 in neuroblastoma cells". Int. J. Oncol. 24 (6): 1407–12. doi:10.3892/ijo.24.6.1407 (neaktivno 31. 10. 2021). PMID 15138581.CS1 održavanje: DOI nije aktivan od 2021 (link)
• Barbashina V, Salazar P, Holland EC, et al. (2005). "Allelic losses at 1p36 and 19q13 in gliomas: correlation with histologic classification, definition of a 150-kb minimal deleted region on 1p36, and evaluation of CAMTA1 as a candidate tumor suppressor gene". Clinical Cancer Research. 11 (3): 1119–28. PMID 15709179.
• Henrich KO, Claas A, Praml C, et al. (2007). "Allelic variants of CAMTA1 and FLJ10737 within a commonly deleted region at 1p36 in neuroblastoma". European Journal of Cancer. 43 (3): 607–16. doi:10.1016/j.ejca.2006.09.023. PMID 17222547.
• Huentelman MJ, Papassotiropoulos A, Craig DW, et al. (2007). "Calmodulin-binding transcription activator 1 (CAMTA1) alleles predispose human episodic memory performance" (PDF). Human Molecular Genetics. 16 (12): 1469–77. doi:10.1093/hmg/ddm097. PMID 17470457.