Šablon:UEFA Evropska liga 2017/18 - 1/16
Prve utakmice odigrale su se 13. i 15. februara, a uzvratne 21. i 22. februara 2018.
| Tim 1 | Rez. | Tim 2 | Prva utakmica | Druga utakmica |
|---|---|---|---|---|
Borussia Dortmund 
|
4–3 |  Atalanta
|
3–2 | 1–1 |
Nice 
|
2–4 |  Lokomotiv Moskva
|
2–3 | 0–1 |
Kopenhagen 
|
1–5 |  Atlético Madrid
|
1–4 | 0–1 |
| Spartak Moskva
|
3–4 | Athletic Bilbao
|
1–3 | 2–1 |
AEK Atina 
|
1–1 (a) |  Dinamo Kijev
|
1–1 | 0–0 |
Celtic 
|
1–3 | Zenit Sankt Peterburg
|
1–0 | 0–3 |
| Napoli
|
3–3 (a) | RB Leipzig
|
1–3 | 2–0 |
Crvena zvezda 
|
0–1 | CSKA Moskva
|
0–0 | 0–1 |
| Lyon
|
4–1 | Villarreal
|
3–1 | 1–0 |
| Real Sociedad
|
3–4 |  Red Bull Salzburg
|
2–2 | 1–2 |
| Partizan
|
1–3 |  Viktoria Plzeň
|
1–1 | 0–2 |
FCSB 
|
2–5 | Lazio
|
1–0 | 1–5 |
Ludogorec Razgrad 
|
0–4 | Milan
|
0–3 | 0–1 |
Astana 
|
4–6 |  Sporting Lisabon
|
1–3 | 3–3 |
Östersund 
|
2–4 |  Arsenal
|
0–3 | 2–1 |
| Marseille
|
3–1 | Braga
|
3–0 | 0–1 |