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ADTRP

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ADTRP
Identifikatori
AliasiADTRP
Vanjski ID-jeviOMIM: 614348 MGI: 1924596 HomoloGene: 13107 GeneCards: ADTRP
Lokacija gena (čovjek)
Hromosom 6 (čovjek)
Hrom.Hromosom 6 (čovjek)[1]
Hromosom 6 (čovjek)
Genomska lokacija za ADTRP
Genomska lokacija za ADTRP
Bend6p24.1Početak11,712,054 bp[1]
Kraj11,807,046 bp[1]
Lokacija gena (miš)
Hromosom 13 (miš)
Hrom.Hromosom 13 (miš)[2]
Hromosom 13 (miš)
Genomska lokacija za ADTRP
Genomska lokacija za ADTRP
Bend13|13 A4Početak41,916,624 bp[2]
Kraj42,001,160 bp[2]
Ontologija gena
Molekularna funkcija• hydrolase activity
Ćelijska komponenta• integral component of membrane
• ćelijska membrana
• Endomembranski sistem
• Kaveole
• cell surface
• membrana
• intracellular anatomical structure
Biološki proces• GO:1901313 positive regulation of gene expression
• negative regulation of blood coagulation
• long-chain fatty acid catabolic process
• cellular response to steroid hormone stimulus
• positive regulation of protein phosphorylation
• cell migration involved in sprouting angiogenesis
• negative regulation of leukocyte migration
• negative regulation of extracellular matrix constituent secretion
• protein kinase B signaling
• negative regulation of protein secretion
• cellular response to oxidised low-density lipoprotein particle stimulus
• negative regulation of leukocyte cell-cell adhesion
• negative regulation of lymphocyte migration
Izvori:Amigo / QuickGO
Ortolozi
VrsteČovjekMiš
Entrez

84830

109254

Ensembl

ENSG00000111863

ENSMUSG00000058022

UniProt

Q96IZ2

Q8C138

RefSeq (mRNK)

NM_001143948
NM_032744

NM_001145875
NM_175417

RefSeq (bjelančevina)

NP_001137420
NP_116133

NP_001139347
NP_780626

Lokacija (UCSC)Chr 6: 11.71 – 11.81 MbChr 13: 41.92 – 42 Mb
PubMed pretraga[3][4]
Wikipodaci
Pogledaj/uredi – čovjekPogledaj/uredi – miš

Androgeno ovisni TFPI-regulirajući protein jest protein koji je kod ljudi kodiran genom ADTRP.[5]

Aminokiselinska sekvenca

[uredi | uredi izvor]

Dužina polipeptidnog lanca je 230 aminokiselina, а molekulska težina 26.842 Da.[6]

1020304050
MTKTSTCIYHFLVLSWYTFLNYYISQEGKDEVKPKILANGARWKYMTLLN
LLLQTIFYGVTCLDDVLKRTKGGKDIKFLTAFRDLLFTTLAFPVSTFVFL
AFWILFLYNRDLIYPKVLDTVIPVWLNHAMHTFIFPITLAEVVLRPHSYP
SKKTGLTLLAAASIAYISRILWLYFETGTWVYPVFAKLSLLGLAAFFSLS
YVFIASIYLLGEKLNHWKWGDMRQPRKKRK

Reference

[uredi | uredi izvor]
  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000111863 - Ensembl, maj 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000058022 - Ensembl, maj 2017
  3. ↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ↑ "Entrez Gene: Androgen-dependent TFPI-regulating protein". Pristupljeno 7. 2. 2013.
  6. ↑ "UniProt, Q96IZ2" (jezik: engleski). Pristupljeno 30. 9. 2021.
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