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Protein 70 sa upredenom zavojnicom je protein koji je kod ljudi kodiran genom CCDC70 . Gen nalazi se na dugom (q) kraku hromosoma 13, pozicija 13q14.3 , od 51,861,969 bp – 51,866,232 baznog para (bp)[5] [6]
Dužina polipeptidnog lanca je 233 aminokiseline , a molekulska težina 287.67 Da .[7]
Simboli
10 20 30 40 50 MATPPFRLIR KMFSFKVSRW MGLACFRSLA ASSPSIRQKK LMHKLQEEKA FREEMKIFRE KIEDFREEMW TFRGKIHAFR GQILGFWEEE RPFWEEEKTF WKEEKSFWEM EKSFREEEKT FWKKYRTFWK EDKAFWKEDN ALWERDRNLL QEDKALWEEE KALWVEERAL LEGEKALWED KTSLWEEENA LWEEERAFWM ENNGHIAGEQ MLEDGPHNAN RGQRLLAFSR GRA
^ a b c GRCh38: Ensembl release 89: ENSG00000123171 - Ensembl , maj 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000017049 - Ensembl , maj 2017^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Bocher M, Blocker H, Bauersachs S, Blum H, Lauber J, Dusterhoft A, Beyer A, Kohrer K, Strack N, Mewes HW, Ottenwalder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A (Mar 2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs" . Genome Res . 11 (3): 422–35. doi :10.1101/gr.GR1547R . PMC 311072 PMID 11230166 . ^ "Entrez Gene: CCDC70 coiled-coil domain containing 70" .^ "UniProt, Q6NSX1" . Pristupljeno 11. 9. 2017 .
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121–7. doi :10.1101/gr.2596504 . PMC 528928 PMID 15489334 . Suzuki Y, Yamashita R, Shirota M, et al. (2004). "Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions" . Genome Res . 14 (9): 1711–8. doi :10.1101/gr.2435604 . PMC 515316 PMID 15342556 . Dunham A, Matthews LH, Burton J, et al. (2004). "The DNA sequence and analysis of human chromosome 13" . Nature . 428 (6982): 522–8. doi :10.1038/nature02379 . PMC 2665288 PMID 15057823 . Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs" . Nat. Genet . 36 (1): 40–5. doi :10.1038/ng1285 PMID 14702039 . Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903. doi :10.1073/pnas.242603899 . PMC 139241 PMID 12477932 . Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing" . EMBO Rep . 1 (3): 287–92. doi :10.1093/embo-reports/kvd058 . PMC 1083732 PMID 11256614 . Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene . 200 (1–2): 149–56. doi :10.1016/S0378-1119(97)00411-3 . PMID 9373149 . Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene . 138 (1–2): 171–4. doi :10.1016/0378-1119(94)90802-8 . PMID 8125298 .
