Idi na sadržaj

CLUH

S Wikipedije, slobodne enciklopedije
CLUH
Identifikatori
AliasiCLUH
Vanjski ID-jeviOMIM: 616184 MGI: 1921398 HomoloGene: 9063 GeneCards: CLUH
Lokacija gena (čovjek)
Hromosom 17 (čovjek)
Hrom.Hromosom 17 (čovjek)[1]
Hromosom 17 (čovjek)
Genomska lokacija za CLUH
Genomska lokacija za CLUH
Bend17p13.3Početak2,689,386 bp[1]
Kraj2,712,663 bp[1]
Lokacija gena (miš)
Hromosom 11 (miš)
Hrom.Hromosom 11 (miš)[2]
Hromosom 11 (miš)
Genomska lokacija za CLUH
Genomska lokacija za CLUH
Bend11 B5|11Početak74,540,321 bp[2]
Kraj74,561,673 bp[2]
Ontologija gena
Molekularna funkcija• mRNA binding
• vezivanje sa RNK
Ćelijska komponenta• citoplazma
Biološki proces• intracellular distribution of mitochondria
• mitochondrion organization
Izvori:Amigo / QuickGO
Ortolozi
VrsteČovjekMiš
Entrez

23277

74148

Ensembl

ENSG00000132361

ENSMUSG00000020741

UniProt

O75153

Q5SW19

RefSeq (mRNK)

NM_015229

NM_001081158
NM_001368711

RefSeq (bjelančevina)

NP_056044
NP_001353590
NP_001353591

NP_001074627
NP_001355640

Lokacija (UCSC)Chr 17: 2.69 – 2.71 MbChr 11: 74.54 – 74.56 Mb
PubMed pretraga[3][4]
Wikipodaci
Pogledaj/uredi – čovjekPogledaj/uredi – miš

Klasterirani mitohondrijski (cluA/CLU1) homolog je protein koji je kod ljudi koditran genom CLUH.[5]

Dužina polipeptidnog lanca je 1.309 aminokiselina, sa molekulskom težinom od 146.670[6].

Aminokiselinska sekvenca

Simboli

C: Cistein
D: Asparaginska kiselina
E: Glutaminska kiselina
F: Fenilalanin
G: Glicin
H: Histidin
I: Izoleucin
K: Lizin
L: Leucin
M: Metionin
N: Asparagin
P: Prolin
Q: Glutamin
R: Arginin
S: Serin
T: Treonin
V: Valin
W: Triptofan
Y: Tirozin

1020304050
MLLNGDCPESLKKEAAAAEPPRENGLDEAGPGDETTGQEVIVIQDTGFSV
KILAPGIEPFSLQVSPQEMVQEIHQVLMDREDTCHRTCFSLHLDGNVLDH
FSELRSVEGLQEGSVLRVVEEPYTVREARIHVRHVRDLLKSLDPSDAFNG
VDCNSLSFLSVFTDGDLGDSGKRKKGLEMDPIDCTPPEYILPGSRERPLC
PLQPQNRDWKPLQCLKVLTMSGWNPPPGNRKMHGDLMYLFVITAEDRQVS
ITASTRGFYLNQSTAYHFNPKPASPRFLSHSLVELLNQISPTFKKNFAVL
QKKRVQRHPFERIATPFQVYSWTAPQAEHAMDCVRAEDAYTSRLGYEEHI
PGQTRDWNEELQTTRELPRKNLPERLLRERAIFKVHSDFTAAATRGAMAV
IDGNVMAINPSEETKMQMFIWNNIFFSLGFDVRDHYKDFGGDVAAYVAPT
NDLNGVRTYNAVDVEGLYTLGTVVVDYRGYRVTAQSIIPGILERDQEQSV
IYGSIDFGKTVVSHPRYLELLERTSRPLKILRHQVLNDRDEEVELCSSVE
CKGIIGNDGRHYILDLLRTFPPDLNFLPVPGEELPEECARAGFPRAHRHK
LCCLRQELVDAFVEHRYLLFMKLAALQLMQQNASQLETPSSLENGGPSSL
ESKSEDPPGQEAGSEEEGSSASGLAKVKELAETIAADDGTDPRSREVIRN
ACKAVGSISSTAFDIRFNPDIFSPGVRFPESCQDEVRDQKQLLKDAAAFL
LSCQIPGLVKDCMEHAVLPVDGATLAEVMRQRGINMRYLGKVLELVLRSP
ARHQLDHVFKIGIGELITRSAKHIFKTYLQGVELSGLSAAISHFLNCFLS
SYPNPVAHLPADELVSKKRNKRRKNRPPGAADNTAWAVMTPQELWKNICQ
EAKNYFDFDLECETVDQAVETYGLQKITLLREISLKTGIQVLLKEYSFDS
RHKPAFTEEDVLNIFPVVKHVNPKASDAFHFFQSGQAKVQQGFLKEGCEL
INEALNLFNNVYGAMHVETCACLRLLARLHYIMGDYAEALSNQQKAVLMS
ERVMGTEHPNTIQEYMHLALYCFASSQLSTALSLLYRARYLMLLVFGEDH
PEMALLDNNIGLVLHGVMEYDLSLRFLENALAVSTKYHGPKALKVALSHH
LVARVYESKAEFRSALQHEKEGYTIYKTQLGEDHEKTKESSEYLKCLTQQ
AVALQRTMNEIYRNGSSANIPPLKFTAPSMASVLEQLNVINGILFIPLSQ
KDLENLKAEVARRHQLQEASRNRDRAEEPMATEPAPAGAPGDLGSQPPAA
KDPSPSVQG

Reference

[uredi | uredi izvor]
  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000132361 - Ensembl, maj 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000020741 - Ensembl, maj 2017
  3. ↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ↑ "Entrez Gene: Clustered mitochondria (cluA/CLU1) homolog". Pristupljeno 15. 4. 2013.
  6. ↑ "UniProt, O75153". Pristupljeno September 12, 2017.
Preuzeto iz "https://bs.wikipedia.org/w/index.php?title=CLUH&oldid=3327822"