NRSN1

NRSN1
Identifikatori
Aliasi	NRSN1
Vanjski ID-jevi	OMIM: 616630 MGI: 894662 HomoloGene: 7597 GeneCards: NRSN1
Lokacija gena (čovjek)
Hrom.	Hromosom 6 (čovjek)
Kraj	24,154,900 bp
Lokacija gena (miš)
Hrom.	Hromosom 13 (miš)
Kraj	25,454,485 bp
Ontologija gena
Molekularna funkcija	• GO:0001948, GO:0016582 vezivanje za proteine;
Ćelijska komponenta	• growth cone; • transport vesicle; • membrana; • integral component of membrane; • neuronal cell body; • neuron projection; • GO:0016023 citoplazmatska vezikula;
Biološki proces	• nervous system development;
	Izvori:Amigo / QuickGO
Ortolozi
	140767
	22360
	ENSG00000152954
	ENSMUSG00000048978
	Q8IZ57
	P97799
	NM_080723
	NM_009513
	NP_542454
	NP_033539
	Wikipodaci
Pogledaj/uredi – čovjek	Pogledaj/uredi – miš

Neurenzin-1 jest protein koji je kod ljudi kodiran genom NRSN1.^[5]^[6]

Aminokiselinska sekvenca[uredi | uredi izvor]

Dužina polipeptidnog lanca je 195 aminokiselina, а molekulska težina 21.475 Da.^[7].

C: Cistein

D: Asparaginska kiselina

E: Glutaminska kiselina

F: Fenilalanin

G: Glicin

H: Histidin

I: Izoleucin

K: Lizin

L: Leucin

M: Metionin

N: Asparagin

P: Prolin

Q: Glutamin

R: Arginin

S: Serin

T: Treonin

V: Valin

W: Triptofan

Y: Tirozin

10	20	30	40	50
MSSCSNVCGS	RQAQAAAEGG	YQRYGVRSYL	HQFYEDCTAS	IWEYEDDFQI
QRSPNRWSSV	FWKVGLISGT	VFVILGLTVL	AVGFLVPPKI	EAFGEADFVV
VDTHAVQFNS	ALDMYKLAGA	VLFCIGGTSM	AGCLLMSVFV	KSYSKEEKFL
QQKFKERIAD	IKAHTQPVTK	APGPGETKIP	VTLSRVQNVQ	PLLAT

Reference[uredi | uredi izvor]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000152954 - Ensembl, maj 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000048978 - Ensembl, maj 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Cheng C, Xu J, Ye X, Dai J, Wu Q, Zeng L, Wang L, Zhao W, Ji C, Gu S, Xie Y, Mao Y (Dec 2002). "Cloning, expression and characterization of a novel human VMP gene". Mol Biol Rep. 29 (3): 281–6. doi:10.1023/A:1020402410522. PMID 12463420. S2CID 21283094.
^ "Entrez Gene: NRSN1 neurensin 1".
^ "UniProt, Q8IZ57" (jezik: engleski). Pristupljeno 4. 10. 2021.

Dopunska luteratura[uredi | uredi izvor]

Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6". Nature. 425 (6960): 805–11. Bibcode:2003Natur.425..805M. doi:10.1038/nature02055. PMID 14574404.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
Hecht HJ, Szardenings M, Collins J, Schomburg D (1991). "Three-dimensional structure of the complexes between bovine chymotrypsinogen A and two recombinant variants of human pancreatic secretory trypsin inhibitor (Kazal-type)". J. Mol. Biol. 220 (3): 711–22. doi:10.1016/0022-2836(91)90112-J. PMID 1870127.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000152954 - Ensembl, maj 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000048978 - Ensembl, maj 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid12463420-5] Cheng C, Xu J, Ye X, Dai J, Wu Q, Zeng L, Wang L, Zhao W, Ji C, Gu S, Xie Y, Mao Y (Dec 2002). "Cloning, expression and characterization of a novel human VMP gene". Mol Biol Rep. 29 (3): 281–6. doi:10.1023/A:1020402410522. PMID 12463420. S2CID 21283094.

[entrez-6] "Entrez Gene: NRSN1 neurensin 1".

[UniProt-7] "UniProt, Q8IZ57" (jezik: engleski). Pristupljeno 4. 10. 2021.

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