OTUD7B
Protein 7B sa domenom OTU jest protein koji je kod ljudi kodiran genom OTUD7B sa hromosoma 1.[5][6]
Aminokiselinska sekvenca[uredi | uredi izvor]
Dužina polipeptidnog lanca je 843 aminokiseline, a molekulska težina 92.526 Da.[7]
| 10 | 20 | 30 | 40 | 50 | ||||
|---|---|---|---|---|---|---|---|---|
| MTLDMDAVLS | DFVRSTGAEP | GLARDLLEGK | NWDVNAALSD | FEQLRQVHAG | ||||
| NLPPSFSEGS | GGSRTPEKGF | SDREPTRPPR | PILQRQDDIV | QEKRLSRGIS | ||||
| HASSSIVSLA | RSHVSSNGGG | GGSNEHPLEM | PICAFQLPDL | TVYNEDFRSF | ||||
| IERDLIEQSM | LVALEQAGRL | NWWVSVDPTS | QRLLPLATTG | DGNCLLHAAS | ||||
| LGMWGFHDRD | LMLRKALYAL | MEKGVEKEAL | KRRWRWQQTQ | QNKESGLVYT | ||||
| EDEWQKEWNE | LIKLASSEPR | MHLGTNGANC | GGVESSEEPV | YESLEEFHVF | ||||
| VLAHVLRRPI | VVVADTMLRD | SGGEAFAPIP | FGGIYLPLEV | PASQCHRSPL | ||||
| VLAYDQAHFS | ALVSMEQKEN | TKEQAVIPLT | DSEYKLLPLH | FAVDPGKGWE | ||||
| WGKDDSDNVR | LASVILSLEV | KLHLLHSYMN | VKWIPLSSDA | QAPLAQPESP | ||||
| TASAGDEPRS | TPESGDSDKE | SVGSSSTSNE | GGRRKEKSKR | DREKDKKRAD | ||||
| SVANKLGSFG | KTLGSKLKKN | MGGLMHSKGS | KPGGVGTGLG | GSSGTETLEK | ||||
| KKKNSLKSWK | GGKEEAAGDG | PVSEKPPAES | VGNGGSKYSQ | EVMQSLSILR | ||||
| TAMQGEGKFI | FVGTLKMGHR | HQYQEEMIQR | YLSDAEERFL | AEQKQKEAER | ||||
| KIMNGGIGGG | PPPAKKPEPD | AREEQPTGPP | AESRAMAFST | GYPGDFTIPR | ||||
| PSGGGVHCQE | PRRQLAGGPC | VGGLPPYATF | PRQCPPGRPY | PHQDSIPSLE | ||||
| PGSHSKDGLH | RGALLPPPYR | VADSYSNGYR | EPPEPDGWAG | GLRGLPPTQT | ||||
| KCKQPNCSFY | GHPETNNFCS | CCYREELRRR | EREPDGELLV | HRF |
Reference[uredi | uredi izvor]
- ^ a b c GRCh38: Ensembl release 89: ENSG00000264522 - Ensembl, maj 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000038495 - Ensembl, maj 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Evans PC, Taylor ER, Coadwell J, Heyninck K, Beyaert R, Kilshaw PJ (Jul 2001). "Isolation and characterization of two novel A20-like proteins". Journal of Biochemistry. 357 (Pt 3): 617–23. doi:10.1042/0264-6021:3570617. PMC 1221992. PMID 11463333.
- ^ "Entrez Gene: OTUD7B OTU domain containing 7B".
- ^ "UniProt, Q6GQQ9" (jezik: engleski). Pristupljeno 15. 12. 2021.
Dopunska literatura[uredi | uredi izvor]
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Research. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Suzuki Y, Yamashita R, Shirota M, et al. (2004). "Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions". Genome Res. 14 (9): 1711–8. doi:10.1101/gr.2435604. PMC 515316. PMID 15342556.
- Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proceedings of the National Academy of Sciences of the United States of America. 101 (33): 12130–5. Bibcode:2004PNAS..10112130B. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
- Evans PC, Ovaa H, Hamon M, et al. (2004). "Zinc-finger protein A20, a regulator of inflammation and cell survival, has de-ubiquitinating activity". Biochem. J. 378 (Pt 3): 727–34. doi:10.1042/BJ20031377. PMC 1224040. PMID 14748687.
- Evans PC, Smith TS, Lai MJ, et al. (2003). "A novel type of deubiquitinating enzyme". Journal of Biological Chemistry. 278 (25): 23180–6. doi:10.1074/jbc.M301863200. PMID 12682062.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Heyninck K, Beyaert R (1999). "The cytokine-inducible zinc finger protein A20 inhibits IL-1-induced NF-kappaB activation at the level of TRAF6". FEBS Letters. 442 (2–3): 147–50. doi:10.1016/S0014-5793(98)01645-7. PMID 9928991.