S Wikipedije, slobodne enciklopedije
Mitohondrijska peptid-deformilaza je enzim koji je kod ljudi kodiran genom PDF .[5] [6] [7]
Dužina polipeptidnog lanca je 243 aminokiseline , a molekulska težina
27.013 Da [8]
Simboli
10 20 30 40 50 MARLWGALSL WPLWAAVPWG GAAAVGVRAC SSTAAPDGVE GPALRRSYWR HLRRLVLGPP EPPFSHVCQV GDPVLRGVAA PVERAQLGGP ELQRLTQRLV QVMRRRRCVG LSAPQLGVPR QVLALELPEA LCRECPPRQR ALRQMEPFPL RVFVNPSLRV LDSRLVTFPE GCESVAGFLA CVPRFQAVQI SGLDPNGEQV VWQASGWAAR IIQHEMDHLQ GCLFIDKMDS RTFTNVYWMK VND
^ a b c GRCh38: Ensembl release 89: ENSG00000258429 - Ensembl , maj 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000078931 - Ensembl , maj 2017^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ Giglione C, Serero A, Pierre M, Boisson B, Meinnel T (Nov 2000). "Identification of eukaryotic peptide deformylases reveals universality of N-terminal protein processing mechanisms" . EMBO J . 19 (21): 5916–29. doi :10.1093/emboj/19.21.5916 . PMC 305796 PMID 11060042 . ^ Lee MD, She Y, Soskis MJ, Borella CP, Gardner JR, Hayes PA, Dy BM, Heaney ML, Philips MR, Bornmann WG, Sirotnak FM, Scheinberg DA (Oct 2004). "Human mitochondrial peptide deformylase, a new anticancer target of actinonin-based antibiotics" . J Clin Invest . 114 (8): 1107–16. doi :10.1172/JCI22269 . PMC 522256 PMID 15489958 . ^ "Entrez Gene: PDF peptide deformylase (mitochondrial)" .^ "UniProt, Q9HBH1" . Pristupljeno 8. 7. 2021 .
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121–7. doi :10.1101/gr.2596504 . PMC 528928 PMID 15489334 . Lee MD, Antczak C, Li Y, et al. (2004). "A new human peptide deformylase inhibitable by actinonin". Biochem. Biophys. Res. Commun . 312 (2): 309–15. doi :10.1016/j.bbrc.2003.10.123 . PMID 14637138 . Serero A, Giglione C, Sardini A, et al. (2004). "An unusual peptide deformylase features in the human mitochondrial N-terminal methionine excision pathway" . J. Biol. Chem . 278 (52): 52953–63. doi :10.1074/jbc.M309770200 PMID 14532271 . Nguyen KT, Hu X, Colton C, et al. (2003). "Characterization of a human peptide deformylase: implications for antibacterial drug design". Biochemistry . 42 (33): 9952–8. doi :10.1021/bi0346446 . PMID 12924944 . Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903. doi :10.1073/pnas.242603899 . PMC 139241 PMID 12477932 . Chagnon P, Michaud J, Mitchell G, et al. (2003). "A missense mutation (R565W) in cirhin (FLJ14728) in North American Indian childhood cirrhosis" . Am. J. Hum. Genet . 71 (6): 1443–9. doi :10.1086/344580 . PMC 378590 PMID 12417987 .
