STRBP
Spermatidni perijedarni RNK-vezujući protein je protein koji je kod ljudi kodiran genom STRBP.[5]
Aminokiselinska sekvenca[uredi | uredi izvor]
Dužina polipeptidnog lanca je 672 aminokiseline, а molekulska težina 73.653 Da.[6]
| 10 | 20 | 30 | 40 | 50 | ||||
|---|---|---|---|---|---|---|---|---|
| MRSIRSFAND | DRHVMVKHST | IYPSPEELEA | VQNMVSTVEC | ALKHVSDWLD | ||||
| ETNKGTKTEG | ETEVKKDEAG | ENYSKDQGGR | TLCGVMRIGL | VAKGLLIKDD | ||||
| MDLELVLMCK | DKPTETLLNT | VKDNLPIQIQ | KLTEEKYQVE | QCVNEASIII | ||||
| RNTKEPTLTL | KVILTSPLIR | DELEKKDGEN | VSMKDPPDLL | DRQKCLNALA | ||||
| SLRHAKWFQA | RANGLKSCVI | VLRILRDLCN | RVPTWAPLKG | WPLELICEKS | ||||
| IGTCNRPLGA | GEALRRVMEC | LASGILLPGG | PGLHDPCERD | PTDALSYMTI | ||||
| QQKEDITHSA | QHALRLSAFG | QIYKVLEMDP | LPSSKPFQKY | SWSVTDKEGA | ||||
| GSSALKRPFE | DGLGDDKDPN | KKMKRNLRKI | LDSKAIDLMN | ALMRLNQIRP | ||||
| GLQYKLLSQS | GPVHAPVFTM | SVDVDGTTYE | ASGPSKKTAK | LHVAVKVLQA | ||||
| MGYPTGFDAD | IECMSSDEKS | DNESKNETVS | SNSSNNTGNS | TTETSSTLEV | ||||
| RTQGPILTAS | GKNPVMELNE | KRRGLKYELI | SETGGSHDKR | FVMEVEVDGQ | ||||
| KFRGAGPNKK | VAKASAALAA | LEKLFSGPNA | ANNKKKKIIP | QAKGVVNTAV | ||||
| SAAVQAVRGR | GRGTLTRGAF | VGATAAPGYI | APGYGTPYGY | STAAPAYGLP | ||||
| KRMVLLPVMK | FPTYPVPHYS | FF |
Reference[uredi | uredi izvor]
- ^ a b c GRCh38: Ensembl release 89: ENSG00000165209 - Ensembl, maj 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000026915 - Ensembl, maj 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Entrez Gene: STRBP spermatid perinuclear RNA binding protein".
- ^ "UniProt, Q96SI9". Pristupljeno 12. 9. 2021.
Dopunska literatura[uredi | uredi izvor]
- Schumacher JM, Lee K, Edelhoff S, Braun RE (maj 1995). "Spnr, a murine RNA-binding protein that is localized to cytoplasmic microtubules". The Journal of Cell Biology. 129 (4): 1023–32. doi:10.1083/jcb.129.4.1023. PMC 2120489. PMID 7744952.
- Schumacher JM, Artzt K, Braun RE (juli 1998). "Spermatid perinuclear ribonucleic acid-binding protein binds microtubules in vitro and associates with abnormal manchettes in vivo in mice". Biology of Reproduction. 59 (1): 69–76. doi:10.1095/biolreprod59.1.69. PMID 9674995.
- Coolidge CJ, Patton JG (mart 2000). "A new double-stranded RNA-binding protein that interacts with PKR". Nucleic Acids Research. 28 (6): 1407–17. doi:10.1093/nar/28.6.1407. PMC 111047. PMID 10684936.
- Hartley JL, Temple GF, Brasch MA (novembar 2000). "DNA cloning using in vitro site-specific recombination". Genome Research. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
- Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Böcher M, Blöcker H, Bauersachs S, Blum H, Lauber J, Düsterhöft A, Beyer A, Köhrer K, Strack N, Mewes HW, Ottenwälder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A (mart 2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Research. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
- Simpson JC, Wellenreuther R, Poustka A, Pepperkok R, Wiemann S (septembar 2000). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Reports. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
- Pires-daSilva A, Nayernia K, Engel W, Torres M, Stoykova A, Chowdhury K, Gruss P (maj 2001). "Mice deficient for spermatid perinuclear RNA-binding protein show neurologic, spermatogenic, and sperm morphological abnormalities" (PDF). Developmental Biology. 233 (2): 319–28. doi:10.1006/dbio.2001.0169. hdl:11858/00-001M-0000-0012-F717-7. PMID 11336498.
- Wiemann S, Arlt D, Huber W, Wellenreuther R, Schleeger S, Mehrle A, Bechtel S, Sauermann M, Korf U, Pepperkok R, Sültmann H, Poustka A (oktobar 2004). "From ORFeome to biology: a functional genomics pipeline". Genome Research. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
- Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (oktobar 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
- Mehrle A, Rosenfelder H, Schupp I, del Val C, Arlt D, Hahne F, Bechtel S, Simpson J, Hofmann O, Hide W, Glatting KH, Huber W, Pepperkok R, Poustka A, Wiemann S (januar 2006). "The LIFEdb database in 2006". Nucleic Acids Research. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.