THRAP3

THRAP3
Identifikatori
Aliasi	THRAP3
Vanjski ID-jevi	OMIM: 603809 MGI: 2442637 HomoloGene: 31289 GeneCards: THRAP3
Lokacija gena (čovjek) Hrom. Hromosom 1 (čovjek) Bend 1p34.3 Početak 36,224,416 bp Kraj 36,305,357 bp
Lokacija gena (miš) Hrom. Hromosom 4 (miš) Bend 4|4 D2.2 Početak 126,164,082 bp Kraj 126,202,760 bp
Obrazac RNK ekspresije Više referentnih podataka o ekspresiji
Ontologija gena Molekularna funkcija • nucleotide binding • GO:0001105 transcription coactivator activity • GO:0001104 transcription coregulator activity • thyroid hormone receptor binding • phosphoprotein binding • core promoter sequence-specific DNA binding • GO:0001948, GO:0016582 vezivanje za proteine • nuclear receptor coactivator activity • ATP binding • vitamin D receptor binding • vezivanje sa RNK • GO:0000980 RNA polymerase II cis-regulatory region sequence-specific DNA binding • signaling receptor activity Ćelijska komponenta • nuclear speck • mediator complex • exon-exon junction complex • nukleoplazma • Egzosom • jedro Biološki proces • androgen receptor signaling pathway • GO:0009373 regulation of transcription, DNA-templated • positive regulation of mRNA splicing, via spliceosome • rhythmic process • mRNA processing • intracellular steroid hormone receptor signaling pathway • regulation of alternative mRNA splicing, via spliceosome • transcription, DNA-templated • GO:0060469, GO:0009371 positive regulation of transcription, DNA-templated • nuclear-transcribed mRNA catabolic process • mRNA stabilization • Jednodnevni biološki ritam • Prerada RNK • positive regulation of circadian rhythm • transcription initiation from RNA polymerase II promoter • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II Izvori:Amigo / QuickGO
Ortolozi
Vrste	Čovjek	Miš
Entrez	9967	230753
Ensembl	ENSG00000054118	ENSMUSG00000043962
UniProt	Q9Y2W1	Q569Z6
RefSeq (mRNK)	NM_005119 NM_001321471 NM_001321473	NM_146153 NM_001356455 NM_001356456
RefSeq (bjelančevina)	NP_001308400 NP_001308402 NP_005110	NP_666265 NP_001343384 NP_001343385
Lokacija (UCSC)	Chr 1: 36.22 – 36.31 Mb	Chr 4: 126.16 – 126.2 Mb
PubMed pretraga
Wikipodaci
Pogledaj/uredi – čovjek Pogledaj/uredi – miš

Protein 3 pridružen receptoru tireoidnog hormona jest protein koji je kod ljudi kodiran genom THRAP3 sa hromosoma 1.

Aminokiselinska sekvenca

Dužina polipeptidnog lanca je 955 aminokiselina, a molekulska težina Da. 108 666

• C: Cistein
• D: Asparaginska kiselina
• E: Glutaminska kiselina
• F: Fenilalanin
• G: Glicin
• H: Histidin
• I: Izoleucin
• K: Lizin
• L: Leucin
• M: Metionin
• N: Asparagin
• P: Prolin
• Q: Glutamin
• R: Arginin
• S: Serin
• T: Treonin
• V: Valin
• W: Triptofan
• Y: Tirozin

10		20		30		40		50
MSKTNKSKSG		SRSSRSRSAS		RSRSRSFSKS		RSRSRSLSRS		RKRRLSSRSR
SRSYSPAHNR		ERNHPRVYQN		RDFRGHNRGY		RRPYYFRGRN		RGFYPWGQYN
RGGYGNYRSN		WQNYRQAYSP		RRGRSRSRSP		KRRSPSPRSR		SHSRNSDKSS
SDRSRRSSSS		RSSSNHSRVE		SSKRKSAKEK		KSSSKDSRPS		QAAGDNQGDE
AKEQTFSGGT		SQDTKASESS		KPWPDATYGT		GSASRASAVS		ELSPRERSPA
LKSPLQSVVV		RRRSPRPSPV		PKPSPPLSST		SQMGSTLPSG		AGYQSGTHQG
QFDHGSGSLS		PSKKSPVGKS		PPSTGSTYGS		SQKEESAASG		GAAYTKRYLE
EQKTENGKDK		EQKQTNTDKE		KIKEKGSFSD		TGLGDGKMKS		DSFAPKTDSE
KPFRGSQSPK		RYKLRDDFEK		KMADFHKEEM		DDQDKDKAKG		RKESEFDDEP
KFMSKVIGAN		KNQEEEKSGK		WEGLVYAPPG		KEKQRKTEEL		EEESFPERSK
KEDRGKRSEG		GHRGFVPEKN		FRVTAYKAVQ		EKSSSPPPRK		TSESRDKLGA
KGDFPTGKSS		FSITREAQVN		VRMDSFDEDL		ARPSGLLAQE		RKLCRDLVHS
NKKEQEFRSI		FQHIQSAQSQ		RSPSELFAQH		IVTIVHHVKE		HHFGSSGMTL
HERFTKYLKR		GTEQEAAKNK		KSPEIHRRID		ISPSTFRKHG		LAHDEMKSPR
EPGYKAEGKY		KDDPVDLRLD		IERRKKHKER		DLKRGKSRES		VDSRDSSHSR
ERSAEKTEKT		HKGSKKQKKH		RRARDRSRSS		SSSSQSSHSY		KAEEYTEETE
EREESTTGFD		KSRLGTKDFV		GPSERGGGRA		RGTFQFRARG		RGWGRGNYSG
NNNNNSNNDF		QKRNREEEWD		PEYTPKSKKY		YLHDDREGEG		SDKWVSRGRG
RGAFPRGRGR		FMFRKSSTSP		KWAHDKFSGE		EGEIEDDESG		TENREEKDNI
QPTTE

Dopunska literatura

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