ZNRD1

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ZNRD1
Identifikatori
AliasiPOLR1H
Vanjski ID-jeviOMIM: 607525 MGI: 1913386 HomoloGene: 40960 GeneCards: POLR1H
Lokacija gena (čovjek)
Hromosom 6 (čovjek)
Hrom.Hromosom 6 (čovjek)[1]
Hromosom 6 (čovjek)
Genomska lokacija za ZNRD1
Genomska lokacija za ZNRD1
Bend6p22.1Početak30,058,899 bp[1]
Kraj30,064,909 bp[1]
Lokacija gena (miš)
Hromosom 17 (miš)
Hrom.Hromosom 17 (miš)[2]
Hromosom 17 (miš)
Genomska lokacija za ZNRD1
Genomska lokacija za ZNRD1
Bend17|17 B1Početak37,265,248 bp[2]
Kraj37,269,451 bp[2]
Ontologija gena
Molekularna funkcija• DNA-directed 5'-3' RNA polymerase activity
• vezivanje iona cinka
• vezivanje iona metala
• nucleic acid binding
• RNA polymerase I activity
Ćelijska komponenta• Jedarce
• jedro
• nukleoplazma
• RNA polymerase I complex
Biološki proces• transcription initiation from RNA polymerase I promoter
• epigenetic maintenance of chromatin in transcription-competent conformation
• nucleobase-containing compound metabolic process
• transcription, DNA-templated
• mRNA cleavage
• termination of RNA polymerase I transcription
• GO:0001183 transcription elongation from RNA polymerase I promoter
Izvori:Amigo / QuickGO
Ortolozi
VrsteČovjekMiš
Entrez

30834

66136

Ensembl
ENSG00000206502
ENSG00000224859
ENSG00000235443
ENSG00000236949
ENSG00000235176

ENSG00000233795
ENSG00000236808
ENSG00000066379

ENSMUSG00000036315

UniProt

Q9P1U0
Q2L6J2

Q791N7

RefSeq (mRNK)

NM_001278785
NM_001278786
NM_014596
NM_170783

NM_023162
NM_001355422

RefSeq (bjelančevina)
NP_001265714
NP_001265715
NP_055411
NP_740753
NP_001265714.1

NP_001265715.1
NP_055411.1
NP_740753.1

NP_075651
NP_001342351

Lokacija (UCSC)Chr 6: 30.06 – 30.06 MbChr 17: 37.27 – 37.27 Mb
PubMed pretraga[3][4]
Wikipodaci
Pogledaj/uredi – čovjekPogledaj/uredi – miš

Protein cinkovog prsta 14 tipa DHHC jest protein koji je kod ljudi kodiran genom ZDHHC14.[5]

Aminokiselinska sekvenca[uredi | uredi izvor]

Dužina polipeptidnog lanca je 488 aminokiselina, а molekulska težina 53.388 Da.[6]

1020304050
MPPGGGGPMKDCEYSQISTHSSSPMESPHKKKKIAARRKWEVFPGRNKFF
CNGRIMMARQTGVFYLTLVLILVTSGLFFAFDCPYLAVKITPAIPAVAGI
LFFFVMGTLLRTSFSDPGVLPRATPDEAADLERQIDIANGTSSGGYRPPP
RTKEVIINGQTVKLKYCFTCKIFRPPRASHCSLCDNCVERFDHHCPWVGN
CVGKRNYRFFYMFILSLSFLTVFIFAFVITHVILRSQQTGFLNALKDSPA
SVLEAVVCFFSVWSIVGLSGFHTYLISSNQTTNEDIKGSWSNKRGKENYN
PYSYGNIFTNCCVALCGPISPSLIDRRGYIQPDTPQPAAPSNGITMYGAT
QSQSDMCDQDQCIQSTKFVLQAAATPLLQSEPSLTSDELHLPGKPGLGTP
CASLTLGPPTPPASMPNLAEATLADVMPRKDEHMGHQFLTPDEAPSPPRL
LAAGSPLAHSRTMHVLGLASQDSLHEDSVRGLVKLSSV

Reference[uredi | uredi izvor]

  1. ^ a b c ENSG00000224859, ENSG00000235443, ENSG00000236949, ENSG00000235176, ENSG00000233795, ENSG00000236808, ENSG00000066379 GRCh38: Ensembl release 89: ENSG00000206502, ENSG00000224859, ENSG00000235443, ENSG00000236949, ENSG00000235176, ENSG00000233795, ENSG00000236808, ENSG00000066379 - Ensembl, maj 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000036315 - Ensembl, maj 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: Zinc finger, DHHC-type containing 14".
  6. ^ "UniProt, Q8IZN3" (jezik: engleski). Pristupljeno 1. 10. 2021.

Dopunska literatura[uredi | uredi izvor]

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