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Protein ksin aktina sa ponavljanjem 2 jest protein koji je kod ljudi kodiran genom XIRP2 sa hromosoma 2 .[5] [6] [7] [8]
Dužina polipeptidnog lanca je 3 374 aminokiseline , a molekulska težina 382.300 Da .[9]
10 20 30 40 50 MSPESGHSRI FEATAGPNKP ESGFAEDSAA RGEGVSDLHE VVSLKERMAR YQAAVSRGDC RSFSANMMEE SEMCAVPGGL AKVKKQFEDE ITSSRNTFAQ YQYQHQNRSE QEAIHSSQVG TSRSSQEMAR NEQEGSKVQK IDVHGTEMVS HLEKHTEEVN QASQFHQYVQ ETVIDTPEDE EIPKVSTKLL KEQFEKSAQE KILYSDKEMT TPAKQIKTES EYEETFKPSS VVSTSSTSCV STSQRKETST TRYSDHSVTS STLAQINATS SGMTEEFPPP PPDVLQTSVD VTAFSQSPEL PSPPRRLPVP KDVYSKQRNL YELNRLYKHI HPELRKNLEK DYISEVSEIV SSQMNSGSSV SADVQQARYV FENTNDSSQK DLNSEREYLE WDEILKGEVQ SIRWIFENQP LDSINNGSPD EGDISRGIAD QEIIAGGDVK YTTWMFETQP IDTLGAYSSD TVENAEKIPE LARGDVCTAR WMFETRPLDS MNKMHQSQEE SAVTISKDIT GGDVKTVRYM FETQHLDQLG QLHSVDEVHL LQLRSELKEI KGNVKRSIKC FETQPLYVIR DGSGQMLEIK TVHREDVEKG DVRTARWMFE TQPLDTINKD ITEIKVVRGI SMEENVKGGV SKAKWLFETQ PLEKIKESEE VIIEKEKIIG TDVSRKCWMF ETQPLDILKE VPDADSLQRE EIIGGDVQTT KHLFETLPIE ALKDSPDIGK LQKITASEEE KGDVRHQKWI FETQPLEDIR KDKKEYTRTV KLEEVDRGDV KNYTHIFESN NLIKFDASHK IEVEGVTRGA VELNKSLFET TPLYAIQDPL GKYHQVKTVQ QEEIVRGDVR SCRWLFETRP IDQFDESIHK FQIIRGISAQ EIQTGNVKSA KWLFETQPLD SIKYFSDVEE TESKTEQTRD IVKGDVKTCK WLFETQPMES LYEKVSLMTS SEEIHKGDVK TCTWLFETQP LDTIKDDSET AVKLQTVKQE EIQGGDVRTA CFLFETENLD SIQGEEVKEI KPVEMDIQAG DVSSMRYKFE NQSLDSISSS SEEVLKKIKT LKTEDIQKGN VLNCRWLFEN QPIDKIKESQ EGDECVKTVT DIQGGDVRKG CFIFETFSLD EIKEESDYIS TKKTITEEVI QGDVKSYRML FETQPLYAIQ DREGSYHEVT TVKKEEVIHG DVRGTRWLFE TKPLDSINKS ETVYVIKSVT QEDIQKGDVS SVRYRFETQP LDQISEESHN IMPSIDHIQG GNVKTSRQFF ESENFDKNNY IRTVSVNEIQ KGNVKTSTWL FETHTMDELR GEGLEYENIK TVTQEDVQKG DVKQAVWLFE NRTFDSIMEA HKGITKMTKE EIPPSDVKTT TWLFETTPLH EFNETRVEKI EIIGKSIKET LEDLYSQKVI QAPGIIIEAD EIGDVRMAKY KLMNQASPEI QKEEIIRADL RNIMVNLLSK RDCTEREILI SEEEKGNVNL TKTQLLNRST EFHAEKEEIV KGDVQQAIKN LFSEERSVKK GILIQEDEKG DINMTIYCLL HENDGDTIER EEVIGGDVKR TIHNLLSSTS NNKISERAKI DASERGNVQF FTTCIEAGAL DYLKQLHTES NETLTAKKQE GEKEIIGGDV EGTKLLLKKR QSLVERTVSE TDIIPGDVHN TVKVFMTEPQ STFGKIPKEE IIKGDLTSTL NSLSQAVNQK TVTKTEEIIK GNMLATLKSL KESSHRWKES KQPDAIPGDI EKAIECLEKA TNTKTEILKK ELLKDDLETS LRSLKEAQRS FKEVHKEGVI KKDAKAVMAG SSGEQKTDIH QVAVQRNKNS LLQPKPGPFE PAAKWQGGAD TLSQTMGKSC HGNLVEERTE VNLPKAPKGT VKIVIDREQN NDALEKSLRR LSNSHHKSNV LESGDKTGVW TDTTGEQHLR DEYMSRQLTS TVSVKNNLTT KESDRAVREL KKDDVFNSIQ SAGKTVGKQQ TYELRNDHQK MEGFHIKSPK KTKNIKILTD TQSSKPSPTQ HPVSMPVGGT YDLSGDFQKQ TLLKQETKYS NKDIKKKNIN LQPMWQLLPV EQDTSNVTEM KVSEKSHNTF KATNKKRETD VHLKSQDFLM KTNTSTGLKM AMERSLNPIN FNPENNVKES ECPLPPPSPP PPPPSNASSE IEFPLPPPPP LMMFPEKNGF LPSLSTEKIK AEFESFPGLP LPPPPVDEKS ERESSSMFLP PPPPPTPSQK PAHLLSSSAP EKHSGDFMQQ YSQKEASNSQ NSQAKIITGK TGVLPPPTLP KPKLPKHIKD NKNDFSPKVE LATSLSDMEC KITTSKDQKK VMVMTSSEHT ETKQNVISKS LDERKQLSID SANCLSHTVP GTSAPRKKQI APLIKSHSFP ESSGQQNPKP YMRKFKTPLM IAEEKYRQQK EEIEKQKQES SYYNIVKTQS QNQHITEVEK EMPLQKTNEE VSLSGIDSEC TVVQPSPGSQ SNARILGVCS DNQLSTTSPE TVAAKRLHHV LAASEDKDKM KKEVLQSSRD IMQSKSACEI KQSHQECSTQ QTQQKKYLEQ LHLPQSKPIS PNFKVKTIKL PTLDHTLNET DHSYESHKQQ SEIDVQTFTK KQYLKTKKTE ASTECSHKQS LAERHYQLPK KEKRVTVQLP TESIQKNQED KLKMVPRKQR EFSGSDRGKL PGSEEKNQGP SMIGRKEERL ITERKHEHLK NKSAPKVVKQ KVIDAHLDSQ TQNFQQTQIQ TAESKAEHKK LPQPYNSLQE EKCLEVKGIQ EKQVFSNTKD SKQEITQNKS FFSSVKESQR DDGKGALNIV EFLRKREELQ QILSRVKQFE AEPNKSGLKT FQTLLNTIPG WLISEDKREY AVHIAMENNL EKVKEEITHI KTQAEDMLVS YENIIQTAMM SSKTGKPGNK PTSLDETSSK VSNVHVSNNK NSEQKENKIA KEKTVQHQVA AHHEATVRSH VKTHQEIKLD DSNIPPPSLK TRPPSPTFIT IESTARRTEN PTKNELSQSP KKDSYVEPPP RRPMSQKSEI HRANTSPSPP RSRSEQLVRL KDTTAKLSKG AIPCPAATPV PIVEKRSEII MSPATLRRQI KIETRGRDSP PTITIPVNIN HAASGSFRES VDAQEEIRKV EKRATYVHKD GLNSTDHMVP DTESYDAVEI IRKVAVPPRL SEHTQRYEAA NRTVQMAENF VNDPENEINR WFREFEHGPV SEAKSNRRVY AKGETNHNIQ QESRTFCKEE FGLTSLGNTS FTDFSCKHPR ELREKIPVKQ PRICSETRSL SEHFSGMDAF ESQIVESKMK TSSSHSSEAG KSGCDFKHAP PTYEDVIAGH ILDISDSPKE VRKNFQKTWQ ESGRVFKGLG YATADASATE MRTTFQEESA FISEAAAPRQ GNMYTLSKDS LSNGVPSGRQ AEFS
^ a b c GRCh38: Ensembl release 89: ENSG00000163092 - Ensembl , maj 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000027022 - Ensembl , maj 2017^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ Huang HT, Brand OM, Mathew M, Ignatiou C, Ewen EP, McCalmon SA, Naya FJ (Dec 2006). "Myomaxin is a novel transcriptional target of MEF2A that encodes a Xin-related alpha-actinin-interacting protein" . J Biol Chem . 281 (51): 39370–9. doi :10.1074/jbc.M603244200 PMID 17046827 . ^ Sinn HW, Balsamo J, Lilien J, Lin JJ (Aug 2002). "Localization of the novel Xin protein to the adherens junction complex in cardiac and skeletal muscle during development" . Dev Dyn . 225 (1): 1–13. doi :10.1002/dvdy.10131 PMID 12203715 . S2CID 23393425 . ^ Pacholsky D, Vakeel P, Himmel M, Lowe T, Stradal T, Rottner K, Furst DO, van der Ven PF (Oct 2004). "Xin repeats define a novel actin-binding motif" . J Cell Sci . 117 (Pt 22): 5257–68. doi :10.1242/jcs.01406 PMID 15454575 . ^ "Entrez Gene: CMYA3 cardiomyopathy associated 3" .^ "UniProt, A4UGR9" (jezik: engleski). Pristupljeno 17. 11. 2021 .
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes" . Genome Res . 16 (1): 55–65. doi :10.1101/gr.4039406 . PMC 1356129 PMID 16344560 . Blasi F, Bacchelli E, Carone S, et al. (2006). "SLC25A12 and CMYA3 gene variants are not associated with autism in the IMGSAC multiplex family sample" . Eur. J. Hum. Genet . 14 (1): 123–6. doi :10.1038/sj.ejhg.5201444 PMID 16205742 . Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs" . Nat. Genet . 36 (1): 40–5. doi :10.1038/ng1285 PMID 14702039 . Pan PW, Li K, Tuggle CK, et al. (2004). "Sequencing, tissue distribution and physical mapping of the porcine homologue of cardiomyopathy associated 3 (CMYA3)". Anim. Genet . 34 (6): 473–4. doi :10.1046/j.0268-9146.2003.01059.x . PMID 14687087 . Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903. doi :10.1073/pnas.242603899 PMC 139241 PMID 12477932 . 
