PRKY
| PRKY | |||||||||||||||||||||||||
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| Identifikatori | |||||||||||||||||||||||||
| Aliasi | PRKY | ||||||||||||||||||||||||
| Vanjski ID-jevi | OMIM: 400008 GeneCards: PRKY | ||||||||||||||||||||||||
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| Ortolozi | |||||||||||||||||||||||||
| Vrste | Čovjek | Miš | |||||||||||||||||||||||
| Entrez |
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| RefSeq (mRNK) |
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| RefSeq (bjelančevina) |
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| Lokacija (UCSC) | Chr Y: 7.27 – 7.38 Mb | n/a | |||||||||||||||||||||||
| PubMed pretraga | [2] | n/a | |||||||||||||||||||||||
| Wikipodaci | |||||||||||||||||||||||||
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Serin/treonin-protein kinaza PRKY je enzim koji je kod čovjeka kodiran genom PRKY.[3][4] Ovaj gen kodira člana porodice cAMP-ovisnu serin/treonin protein kinazu. Ovaj gen se nalazi na hromozomu Y, blizu granice pseudoautosomne regije. Abnormalna rekombinacija između ovog gena i srodnog gena na hromozomu X čest je uzrok XX muškaraca i XY žene.[4]
Reference
[uredi | uredi izvor]- 1 2 3 GRCh38: Ensembl release 89: ENSG00000099725 - Ensembl, maj 2017
- ↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ↑ Klink A, Schiebel K, Winkelmann M, Rao E, Horsthemke B, Ludecke HJ, Claussen U, Scherer G, Rappold G (Sep 1995). "The human protein kinase gene PKX1 on Xp22.3 displays Xp/Yp homology and is a site of chromosomal instability". Hum Mol Genet. 4 (5): 869–78. doi:10.1093/hmg/4.5.869. PMID 7633447.
- 1 2 "Entrez Gene: PRKY protein kinase, Y-linked".
Dopunska literatura
[uredi | uredi izvor]- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Skaletsky H, Kuroda-Kawaguchi T, Minx PJ, et al. (2003). "The male-specific region of the human Y chromosome is a mosaic of discrete sequence classes". Nature. 423 (6942): 825–37. Bibcode:2003Natur.423..825S. doi:10.1038/nature01722. PMID 12815422.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Jobling MA, Williams GA, Schiebel GA, et al. (1999). "A selective difference between human Y-chromosomal DNA haplotypes". Curr. Biol. 8 (25): 1391–4. doi:10.1016/S0960-9822(98)00020-7. PMID 9889101.
- Schiebel K, Winkelmann M, Mertz A, et al. (1998). "Abnormal XY interchange between a novel isolated protein kinase gene, PRKY, and its homologue, PRKX, accounts for one third of all (Y+)XX males and (Y-)XY females". Hum. Mol. Genet. 6 (11): 1985–9. doi:10.1093/hmg/6.11.1985. PMID 9302280.
- Schiebel K, Mertz A, Winkelmann M, et al. (1997). "FISH localization of the human Y-homolog of protein kinase PRKX (PRKY) to Yp11.2 and two pseudogenes to 15q26 and Xq12→q13". Cytogenet. Cell Genet. 76 (1–2): 49–52. doi:10.1159/000134514. PMID 9154127.
- Gläser B, Hierl T, Taylor K, et al. (1997). "High-resolution fluorescence in situ hybridization of human Y-linked genes on released chromatin". Chromosome Res. 5 (1): 23–30. doi:10.1023/A:1018437301461. PMID 9088640.
