FOXB1

FOXB1
Identifikatori
Aliasi	FOXB1
Vanjski ID-jevi	OMIM: 619961 MGI: 1927549 HomoloGene: 8138 GeneCards: FOXB1
Lokacija gena (čovjek) Hrom. Hromosom 15 (čovjek) Bend 15q22.2 Početak 60,004,234 bp Kraj 60,061,730 bp
Lokacija gena (miš) Hrom. Hromosom 9 (miš) Bend 9 D|9 38.76 cM Početak 69,664,992 bp Kraj 69,668,222 bp
Ontologija gena Molekularna funkcija • vezivanje sa DNK • GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity • GO:0001948, GO:0016582 vezivanje za proteine • sequence-specific DNA binding • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific Ćelijska komponenta • jedro Biološki proces • visual learning • somitogenesis • GO:1904089 negative regulation of neuron apoptotic process • mammillary body development • mammillothalamic axonal tract development • GO:0009373 regulation of transcription, DNA-templated • axon target recognition • mammary gland lobule development • thalamus development • transcription, DNA-templated • floor plate development • telencephalon cell migration • cell migration in diencephalon • inferior colliculus development • spinal cord development • urogenital system development • Laktacija • midbrain development • epithelial cell differentiation involved in mammary gland alveolus development • hypothalamus cell migration • GO:0044324, GO:0003256, GO:1901213, GO:0046019, GO:0046020, GO:1900094, GO:0061216, GO:0060994, GO:1902064, GO:0003258, GO:0072212 regulation of transcription by RNA polymerase II • anatomical structure morphogenesis • Ćelijska diferencijacija Izvori:Amigo / QuickGO
Ortolozi
Vrste	Čovjek	Miš
Entrez	27023	64290
Ensembl	ENSG00000171956	ENSMUSG00000059246
UniProt	Q99853	Q64732
RefSeq (mRNK)	NM_012182	NM_022378
RefSeq (bjelančevina)	NP_036314	NP_071773
Lokacija (UCSC)	Chr 15: 60 – 60.06 Mb	Chr 9: 69.66 – 69.67 Mb
PubMed pretraga
Wikipodaci
Pogledaj/uredi – čovjek Pogledaj/uredi – miš

Viljuškasta kutija B1 ja protein koji je kod ljudi kodiran genom FOXB1.

Aminokiselinska sekvenca

Dužina polipeptidnog lanca je 325 aminokiselina, a molekulska težina 34.978 Da..

10		20		30		40		50
MPRPGRNTYS		DQKPPYSYIS		LTAMAIQSSP		EKMLPLSEIY		KFIMDRFPYY
RENTQRWQNS		LRHNLSFNDC		FIKIPRRPDQ		PGKGSFWALH		PSCGDMFENG
SFLRRRKRFK		VLKSDHLAPS		KPADAAQYLQ		QQAKLRLSAL		AASGTHLPQM
PAAAYNLGGV		AQPSGFKHPF		AIENIIAREY		KMPGGLAFSA		MQPVPAAYPL
PNQLTTMGSS		LGTGWPHVYG		SAGMIDSATP		ISMASGDYSA		YGVPLKPLCH
AAGQTLPAIP		VPIKPTPAAV		PALPALPAPI		PTLLSNSPPS		LSPTSSQTAT
SQSSPATPSE		TLTSPASALH		SVAVH

Simboli

C: Cistein
D: Asparaginska kiselina
E: Glutaminska kiselina
F: Fenilalanin
G: Glicin
H: Histidin
I: Izoleucin
K: Lizin
L: Leucin
M: Metionin
N: Asparagin
P: Prolin
Q: Glutamin
R: Arginin
S: Serin
T: Treonin
V: Valin
W: Triptofan
Y: Tirozin