Idi na sadržaj

SENP7

S Wikipedije, slobodne enciklopedije
SENP7
Dostupne strukture
PDBPretraga ortologa: PDBe RCSB
Spisak PDB ID kodova

3EAY

Identifikatori
AliasiSENP7
Vanjski ID-jeviOMIM: 612846 MGI: 1913565 HomoloGene: 10778 GeneCards: SENP7
Lokacija gena (čovjek)
Hromosom 3 (čovjek)
Hrom.Hromosom 3 (čovjek)[1]
Hromosom 3 (čovjek)
Genomska lokacija za SENP7
Genomska lokacija za SENP7
Bend3q12.3Početak101,324,205 bp[1]
Kraj101,513,241 bp[1]
Lokacija gena (miš)
Hromosom 16 (miš)
Hrom.Hromosom 16 (miš)[2]
Hromosom 16 (miš)
Genomska lokacija za SENP7
Genomska lokacija za SENP7
Bend16|16 C1.1Početak55,868,701 bp[2]
Kraj56,010,375 bp[2]
Obrazac RNK ekspresije
Više referentnih podataka o ekspresiji
Ontologija gena
Molekularna funkcija GO:0070122 peptidase activity
cysteine-type peptidase activity
GO:0001948, GO:0016582 vezivanje za proteine
hydrolase activity
G protein-coupled receptor activity
SUMO-specific endopeptidase activity
Ćelijska komponenta intracellular anatomical structure
jedro
ćelijska membrana
citoplazma
Biološki proces Proteoliza
adenylate cyclase-modulating G protein-coupled receptor signaling pathway
protein desumoylation
Izvori:Amigo / QuickGO
Ortolozi
VrsteČovjekMiš
Entrez
Ensembl
UniProt
RefSeq (mRNK)
NM_001077203
NM_001282801
NM_001282802
NM_001282803
NM_001282804

NM_020654

NM_001003971
NM_001003972
NM_001003973
NM_025483
NM_001304503

NM_001360073

RefSeq (bjelančevina)
NP_001070671
NP_001269730
NP_001269731
NP_001269732
NP_001269733

NP_065705

NP_001003972
NP_001003973
NP_001291432
NP_079759
NP_001347002

Lokacija (UCSC)Chr 3: 101.32 – 101.51 MbChr 16: 55.87 – 56.01 Mb
PubMed pretraga[3][4]
Wikipodaci
Pogledaj/uredi – čovjekPogledaj/uredi – miš

Sentrin-specifična proteaza 7 jest enzim koji je kod ljudi kodiran genom SENP7 sa hromosoma 3.[5][6][7]

Aminokiselinska sekvenca

[uredi | uredi izvor]

Dužina polipeptidnog lanca je 1.050 aminokiselina, а molekulska težina 119.658 Da.[8]

1020304050
MDKRKLGRRPSSSEIITEGKRKKSSSDLSEIRKMLNAKPEDVHVQSPLSK
FRSSERWTLPLQWERSLRNKVISLDHKNKKHIRGCPVTSKSSPERQLKVM
LTNVLWTDLGRKFRKTLPRNDANLCDANKVQSDSLPSTSVDSLETCQKLE
PLRQSLNLSERIPRVILTNVLGTELGRKYIRTPPVTEGSLSDTDNLQSEQ
LSSSSDGSLESYQNLNPHKSCYLSERGSQRSKTVDDNSAKQTAHNKEKRR
KDDGISLLISDTQPEDLNSGSRGCDHLEQESRNKDVKYSDSKVELTLISR
KTKRRLRNNLPDSQYCTSLDKSTEQTKKQEDDSTISTEFEKPSENYHQDP
KLPEEITTKPTKSDFTKLSSLNSQELTLSNATKSASAGSTTETVENSNSI
DIVGISSLVEKDENELNTIEKPILRGHNEGNQSLISAEPIVVSSDEEGPV
EHKSSEILKLQSKQDRETTNENESTSESALLELPLITCESVQMSSELCPY
NPVMENISSIMPSNEMDLQLDFIFTSVYIGKIKGASKGCVTITKKYIKIP
FQVSLNEISLLVDTTHLKRFGLWKSKDDNHSKRSHAILFFWVSSDYLQEI
QTQLEHSVLSQQSKSSEFIFLELHNPVSQREELKLKDIMTEISIISGELE
LSYPLSWVQAFPLFQNLSSKESSFIHYYCVSTCSFPAGVAVAEEMKLKSV
SQPSNTDAAKPTYTFLQKQSSGCYSLSITSNPDEEWREVRHTGLVQKLIV
YPPPPTKGGLGVTNEDLECLEEGEFLNDVIIDFYLKYLILEKASDELVER
SHIFSSFFYKCLTRKENNLTEDNPNLSMAQRRHKRVRTWTRHINIFNKDY
IFVPVNESSHWYLAVICFPWLEEAVYEDFPQTVSQQSQAQQSQNDNKTID
NDLRTTSTLSLSAEDSQSTESNMSVPKKMCKRPCILILDSLKAASVQNTV
QNLREYLEVEWEVKLKTHRQFSKTNMVDLCPKVPKQDNSSDCGVYLLQYV
ESFFKDPIVNFELPIHLEKWFPRHVIKTKREDIRELILKLHLQQQKGSSS

Reference

[uredi | uredi izvor]
  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000138468 - Ensembl, maj 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000052917 - Ensembl, maj 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Nagase T, Kikuno R, Hattori A, Kondo Y, Okumura K, Ohara O (Feb 2001). "Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 7 (6): 347–55. doi:10.1093/dnares/7.6.347. PMID 11214970.
  6. ^ Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Bocher M, Blocker H, Bauersachs S, Blum H, Lauber J, Dusterhoft A, Beyer A, Kohrer K, Strack N, Mewes HW, Ottenwalder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A (Mar 2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
  7. ^ "Entrez Gene: SENP7 SUMO1/sentrin specific peptidase 7".
  8. ^ "UniProt, Q9BQF6" (jezik: engleski). Pristupljeno 9. 11. 2021.

Dopunska literatura

[uredi | uredi izvor]

Vanjski linkovi

[uredi | uredi izvor]