UBR4

UBR4
Identifikatori
Aliasi	UBR4
Vanjski ID-jevi	OMIM: 609890 MGI: 1916366 HomoloGene: 10804 GeneCards: UBR4
Lokacija gena (čovjek)
Hrom.	Hromosom 1 (čovjek)
Kraj	19,210,266 bp
Lokacija gena (miš)
Hrom.	Hromosom 4 (miš)
Kraj	139,216,899 bp
Obrazac RNK ekspresije
	; ;
	Više referentnih podataka o ekspresiji
Ontologija gena
Molekularna funkcija	• vezivanje iona cinka; • GO:0001948, GO:0016582 vezivanje za proteine; • vezivanje iona metala; • calmodulin binding; • GO:0050372 aktivnost sa transferazom ubikvitina; • aktivnost sa transferazom;
Ćelijska komponenta	• integral component of membrane; • centrosom; • citoskelet; • membrana; • jedro; • nukleoplazma; • citoplazma; • citosol; • ćelijska membrana; • specific granule membrane; • tertiary granule membrane; • ficolin-1-rich granule membrane;
Biološki proces	• GO:0022415 viral process; • protein ubiquitination; • neutrophil degranulation; • ubiquitin-dependent protein catabolic process;
	Izvori:Amigo / QuickGO
Ortolozi
	23352
	69116
	ENSG00000127481
	ENSMUSG00000066036
	Q5T4S7
	A2AN08
	NM_020765
	NM_001160319
	NP_065816
	NP_001153791
	Wikipodaci
Pogledaj/uredi – čovjek	Pogledaj/uredi – miš

E3 ubikvitin-protein ligaza UBR4 jest enzim koji je kod ljudi kodiran genom UBR4 sa hromosoma 1.^[5]^[6]^[7]^[8]

Aminokiselinska sekvenca[uredi | uredi izvor]

Dužina polipeptidnog lanca je 5.183 aminokiselina, a molekulska težina 573.841 Da.^[9]

C: Cistein

D: Asparaginska kiselina

E: Glutaminska kiselina

F: Fenilalanin

G: Glicin

H: Histidin

I: Izoleucin

K: Lizin

L: Leucin

M: Metionin

N: Asparagin

P: Prolin

Q: Glutamin

R: Arginin

S: Serin

T: Treonin

V: Valin

W: Triptofan

Y: Tirozin

10	20	30	40	50
MATSGGEEAA	AAAPAPGTPA	TGADTTPGWE	VAVRPLLSAS	YSAFEMKELP
QLVASVIESE	SEILHHEKQY	EPFYSSFVAL	STHYITTVCS	LIPRNQLQSV
AAACKVLIEF	SLLRLENPDE	ACAVSQKHLI	LLIKGLCTGC	SRLDRTEIIT
FTAMMKSAKL	PQTVKTLSDV	EDQKELASPV	SPELRQKEVQ	MNFLNQLTSV
FNPRTVASQP	ISTQTLVEGE	NDEQSSTDQA	SAIKTKNVFI	AQNVASLQEL
GGSEKLLRVC	LNLPYFLRYI	NRFQDAVLAN	SFFIMPATVA	DATAVRNGFH
SLVIDVTMAL	DTLSLPVLEP	LNPSRLQDVT	VLSLSCLYAG	VSVATCMAIL
HVGSAQQVRT	GSTSSKEDDY	ESDAATIVQK	CLEIYDMIGQ	AISSSRRAGG
EHYQNFQLLG	AWCLLNSLFL	ILNLSPTALA	DKGKEKDPLA	ALRVRDILSR
TKEGVGSPKL	GPGKGHQGFG	VLSVILANHA	IKLLTSLFQD	LQVEALHKGW
ETDGPPAALS	IMAQSTSIQR	IQRLIDSVPL	MNLLLTLLST	SYRKACVLQR
QRKGSMSSDA	SASTDSNTYY	EDDFSSTEED	SSQDDDSEPI	LGQWFEETIS
PSKEKAAPPP	PPPPPPLESS	PRVKSPSKQA	PGEKGNILAS	RKDPELFLGL
ASNILNFITS	SMLNSRNNFI	RNYLSVSLSE	HHMATLASII	KEVDKDGLKG
SSDEEFAAAL	YHFNHSLVTS	DLQSPNLQNT	LLQQLGVAPF	SEGPWPLYIH
PQSLSVLSRL	LLIWQHKASA	QGDPDVPECL	KVWDRFLSTM	KQNALQGVVP
SETEDLNVEH	LQMLLLIFHN	FTETGRRAIL	SLFVQIIQEL	SVNMDAQMRF
VPLILARLLL	IFDYLLHQYS	KAPVYLFEQV	QHNLLSPPFG	WASGSQDSNS
RRATTPLYHG	FKEVEENWSK	HFSSDAVPHP	RFYCVLSPEA	SEDDLNRLDS
VACDVLFSKL	VKYDELYAAL	TALLAAGSQL	DTVRRKENKN	VTALEACALQ
YYFLILWRIL	GILPPSKTYI	NQLSMNSPEM	SECDILHTLR	WSSRLRISSY
VNWIKDHLIK	QGMKAEHASS	LLELASTTKC	SSVKYDVEIV	EEYFARQISS
FCSIDCTTIL	QLHEIPSLQS	IYTLDAAISK	VQVSLDEHFS	KMAAETDPHK
SSEITKNLLP	ATLQLIDTYA	SFTRAYLLQN	FNEEGTTEKP	SKEKLQGFAA
VLAIGSSRCK	ANTLGPTLVQ	NLPSSVQTVC	ESWNNINTNE	FPNIGSWRNA
FANDTIPSES	YISAVQAAHL	GTLCSQSLPL	AASLKHTLLS	LVRLTGDLIV
WSDEMNPPQV	IRTLLPLLLE	SSTESVAEIS	SNSLERILGP	AESDEFLARV
YEKLITGCYN	ILANHADPNS	GLDESILEEC	LQYLEKQLES	SQARKAMEEF
FSDSGELVQI	MMATANENLS	AKFCNRVLKF	FTKLFQLTEK	SPNPSLLHLC
GSLAQLACVE	PVRLQAWLTR	MTTSPPKDSD	QLDVIQENRQ	LLQLLTTYIV
RENSQVGEGV	CAVLLGTLTP	MATEMLANGD	GTGFPELMVV	MATLASAGQG
AGHLQLHNAA	VDWLSRCKKY	LSQKNVVEKL	NANVMHGKHV	MILECTCHIM
SYLADVTNAL	SQSNGQGPSH	LSVDGEERAI	EVDSDWVEEL	AVEEEDSQAE
DSDEDSLCNK	LCTFTITQKE	FMNQHWYHCH	TCKMVDGVGV	CTVCAKVCHK
DHEISYAKYG	SFFCDCGAKE	DGSCLALVKR	TPSSGMSSTM	KESAFQSEPR
ISESLVRHAS	TSSPADKAKV	TISDGKVADE	EKPKKSSLCR	TVEGCREELQ
NQANFSFAPL	VLDMLNFLMD	AIQTNFQQAS	AVGSSSRAQQ	ALSELHTVEK
AVEMTDQLMV	PTLGSQEGAF	ENVRMNYSGD	QGQTIRQLIS	AHVLRRVAMC
VLSSPHGRRQ	HLAVSHEKGK	ITVLQLSALL	KQADSSKRKL	TLTRLASAPV
PFTVLSLTGN	PCKEDYLAVC	GLKDCHVLTF	SSSGSVSDHL	VLHPQLATGN
FIIKAVWLPG	SQTELAIVTA	DFVKIYDLCV	DALSPTFYFL	LPSSKIRDVT
FLFNEEGKNI	IVIMSSAGYI	YTQLMEEASS	AQQGPFYVTN	VLEINHEDLK
DSNSQVAGGG	VSVYYSHVLQ	MLFFSYCQGK	SFAATISRTT	LEVLQLFPIN
IKSSNGGSKT	SPALCQWSEV	MNHPGLVCCV	QQTTGVPLVV	MVKPDTFLIQ
EIKTLPAKAK	IQDMVAIRHT	ACNEQQRTTM	ILLCEDGSLR	IYMANVENTS
YWLQPSLQPS	SVISIMKPVR	KRKTATITTR	TSSQVTFPID	FFEHNQQLTD
VEFGGNDLLQ	VYNAQQIKHR	LNSTGMYVAN	TKPGGFTIEI	SNNNSTMVMT
GMRIQIGTQA	IERAPSYIEI	FGRTMQLNLS	RSRWFDFPFT	REEALQADKK
LNLFIGASVD	PAGVTMIDAV	KIYGKTKEQF	GWPDEPPEEF	PSASVSNICP
SNLNQSNGTG	DSDSAAPTTT	SGTVLERLVV	SSLEALESCF	AVGPIIEKER
NKNAAQELAT	LLLSLPAPAS	VQQQSKSLLA	SLHTSRSAYH	SHKDQALLSK
AVQCLNTSSK	EGKDLDPEVF	QRLVITARSI	AIMRPNNLVH	FTESKLPQME
TEGMDEGKEP	QKQLEGDCCS	FITQLVNHFW	KLHASKPKNA	FLAPACLPGL
THIEATVNAL	VDIIHGYCTC	ELDCINTASK	IYMQMLLCPD	PAVSFSCKQA
LIRVLRPRNK	RRHVTLPSSP	RSNTPMGDKD	DDDDDDADEK	MQSSGIPNGG
HIRQESQEQS	EVDHGDFEMV	SESMVLETAE	NVNNGNPSPL	EALLAGAEGF
PPMLDIPPDA	DDETMVELAI	ALSLQQDQQG	SSSSALGLQS	LGLSGQAPSS
SSLDAGTLSD	TTASAPASDD	EGSTAATDGS	TLRTSPADHG	GSVGSESGGS
AVDSVAGEHS	VSGRSSAYGD	ATAEGHPAGP	GSVSSSTGAI	STTTGHQEGD
GSEGEGEGET	EGDVHTSNRL	HMVRLMLLER	LLQTLPQLRN	VGGVRAIPYM
QVILMLTTDL	DGEDEKDKGA	LDNLLSQLIA	ELGMDKKDVS	KKNERSALNE
VHLVVMRLLS	VFMSRTKSGS	KSSICESSSL	ISSATAAALL	SSGAVDYCLH
VLKSLLEYWK	SQQNDEEPVA	TSQLLKPHTT	SSPPDMSPFF	LRQYVKGHAA
DVFEAYTQLL	TEMVLRLPYQ	IKKITDTNSR	IPPPVFDHSW	FYFLSEYLMI
QQTPFVRRQV	RKLLLFICGS	KEKYRQLRDL	HTLDSHVRGI	KKLLEEQGIF
LRASVVTASS	GSALQYDTLI	SLMEHLKACA	EIAAQRTINW	QKFCIKDDSV
LYFLLQVSFL	VDEGVSPVLL	QLLSCALCGS	KVLAALAASS	GSSSASSSSA
PVAASSGQAT	TQSKSSTKKS	KKEEKEKEKD	GETSGSQEDQ	LCTALVNQLN
KFADKETLIQ	FLRCFLLESN	SSSVRWQAHC	LTLHIYRNSS	KSQQELLLDL
MWSIWPELPA	YGRKAAQFVD	LLGYFSLKTP	QTEKKLKEYS	QKAVEILRTQ
NHILTNHPNS	NIYNTLSGLV	EFDGYYLESD	PCLVCNNPEV	PFCYIKLSSI
KVDTRYTTTQ	QVVKLIGSHT	ISKVTVKIGD	LKRTKMVRTI	NLYYNNRTVQ
AIVELKNKPA	RWHKAKKVQL	TPGQTEVKID	LPLPIVASNL	MIEFADFYEN
YQASTETLQC	PRCSASVPAN	PGVCGNCGEN	VYQCHKCRSI	NYDEKDPFLC
NACGFCKYAR	FDFMLYAKPC	CAVDPIENEE	DRKKAVSNIN	TLLDKADRVY
HQLMGHRPQL	ENLLCKVNEA	APEKPQDDSG	TAGGISSTSA	SVNRYILQLA
QEYCGDCKNS	FDELSKIIQK	VFASRKELLE	YDLQQREAAT	KSSRTSVQPT
FTASQYRALS	VLGCGHTSST	KCYGCASAVT	EHCITLLRAL	ATNPALRHIL
VSQGLIRELF	DYNLRRGAAA	MREEVRQLMC	LLTRDNPEAT	QQMNDLIIGK
VSTALKGHWA	NPDLASSLQY	EMLLLTDSIS	KEDSCWELRL	RCALSLFLMA
VNIKTPVVVE	NITLMCLRIL	QKLIKPPAPT	SKKNKDVPVE	ALTTVKPYCN
EIHAQAQLWL	KRDPKASYDA	WKKCLPIRGI	DGNGKAPSKS	ELRHLYLTEK
YVWRWKQFLS	RRGKRTSPLD	LKLGHNNWLR	QVLFTPATQA	ARQAACTIVE
ALATIPSRKQ	QVLDLLTSYL	DELSIAGECA	AEYLALYQKL	ITSAHWKVYL
AARGVLPYVG	NLITKEIARL	LALEEATLST	DLQQGYALKS	LTGLLSSFVE
VESIKRHFKS	RLVGTVLNGY	LCLRKLVVQR	TKLIDETQDM	LLEMLEDMTT
GTESETKAFM	AVCIETAKRY	NLDDYRTPVF	IFERLCSIIY	PEENEVTEFF
VTLEKDPQQE	DFLQGRMPGN	PYSSNEPGIG	PLMRDIKNKI	CQDCDLVALL
EDDSGMELLV	NNKIISLDLP	VAEVYKKVWC	TTNEGEPMRI	VYRMRGLLGD
ATEEFIESLD	STTDEEEDEE	EVYKMAGVMA	QCGGLECMLN	RLAGIRDFKQ
GRHLLTVLLK	LFSYCVKVKV	NRQQLVKLEM	NTLNVMLGTL	NLALVAEQES
KDSGGAAVAE	QVLSIMEIIL	DESNAEPLSE	DKGNLLLTGD	KDQLVMLLDQ
INSTFVRSNP	SVLQGLLRII	PYLSFGEVEK	MQILVERFKP	YCNFDKYDED
HSGDDKVFLD	CFCKIAAGIK	NNSNGHQLKD	LILQKGITQN	ALDYMKKHIP
SAKNLDADIW	KKFLSRPALP	FILRLLRGLA	IQHPGTQVLI	GTDSIPNLHK
LEQVSSDEGI	GTLAENLLEA	LREHPDVNKK	IDAARRETRA	EKKRMAMAMR
QKALGTLGMT	TNEKGQVVTK	TALLKQMEEL	IEEPGLTCCI	CREGYKFQPT
KVLGIYTFTK	RVALEEMENK	PRKQQGYSTV	SHFNIVHYDC	HLAAVRLARG
REEWESAALQ	NANTKCNGLL	PVWGPHVPES	AFATCLARHN	TYLQECTGQR
EPTYQLNIHD	IKLLFLRFAM	EQSFSADTGG	GGRESNIHLI	PYIIHTVLYV
LNTTRATSRE	EKNLQGFLEQ	PKEKWVESAF	EVDGPYYFTV	LALHILPPEQ
WRATRVEILR	RLLVTSQARA	VAPGGATRLT	DKAVKDYSAY	RSSLLFWALV
DLIYNMFKKV	PTSNTEGGWS	CSLAEYIRHN	DMPIYEAADK	ALKTFQEEFM
PVETFSEFLD	VAGLLSEITD	PESFLKDLLN	SVP

Reference[uredi | uredi izvor]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000127481 - Ensembl, maj 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000066036 - Ensembl, maj 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Ota T, Suzuki Y, Nishikawa T, Otsuki T, Sugiyama T, Irie R, Wakamatsu A, Hayashi K, Sato H, Nagai K, Kimura K, Makita H, Sekine M, Obayashi M, Nishi T, Shibahara T, Tanaka T, Ishii S, Yamamoto J, Saito K, Kawai Y, Isono Y, Nakamura Y, Nagahari K, Murakami K, Yasuda T, Iwayanagi T, Wagatsuma M, Shiratori A, Sudo H, Hosoiri T, Kaku Y, Kodaira H, Kondo H, Sugawara M, Takahashi M, Kanda K, Yokoi T, Furuya T, Kikkawa E, Omura Y, Abe K, Kamihara K, Katsuta N, Sato K, Tanikawa M, Yamazaki M, Ninomiya K, Ishibashi T, Yamashita H, Murakawa K, Fujimori K, Tanai H, Kimata M, Watanabe M, Hiraoka S, Chiba Y, Ishida S, Ono Y, Takiguchi S, Watanabe S, Yosida M, Hotuta T, Kusano J, Kanehori K, Takahashi-Fujii A, Hara H, Tanase TO, Nomura Y, Togiya S, Komai F, Hara R, Takeuchi K, Arita M, Imose N, Musashino K, Yuuki H, Oshima A, Sasaki N, Aotsuka S, Yoshikawa Y, Matsunawa H, Ichihara T, Shiohata N, Sano S, Moriya S, Momiyama H, Satoh N, Takami S, Terashima Y, Suzuki O, Nakagawa S, Senoh A, Mizoguchi H, Goto Y, Shimizu F, Wakebe H, Hishigaki H, Watanabe T, Sugiyama A, Takemoto M, Kawakami B, Yamazaki M, Watanabe K, Kumagai A, Itakura S, Fukuzumi Y, Fujimori Y, Komiyama M, Tashiro H, Tanigami A, Fujiwara T, Ono T, Yamada K, Fujii Y, Ozaki K, Hirao M, Ohmori Y, Kawabata A, Hikiji T, Kobatake N, Inagaki H, Ikema Y, Okamoto S, Okitani R, Kawakami T, Noguchi S, Itoh T, Shigeta K, Senba T, Matsumura K, Nakajima Y, Mizuno T, Morinaga M, Sasaki M, Togashi T, Oyama M, Hata H, Watanabe M, Komatsu T, Mizushima-Sugano J, Satoh T, Shirai Y, Takahashi Y, Nakagawa K, Okumura K, Nagase T, Nomura N, Kikuchi H, Masuho Y, Yamashita R, Nakai K, Yada T, Nakamura Y, Ohara O, Isogai T, Sugano S (Dec 2003). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat Genet. 36 (1): 40–45. doi:10.1038/ng1285. PMID 14702039.
^ Nagase T, Kikuno R, Ishikawa KI, Hirosawa M, Ohara O (Apr 2000). "Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 7 (1): 65–73. doi:10.1093/dnares/7.1.65. PMID 10718198.
^ Tasaki T, Mulder LC, Iwamatsu A, Lee MJ, Davydov IV, Varshavsky A, Muesing M, Kwon YT (Aug 2005). "A family of mammalian E3 ubiquitin ligases that contain the UBR box motif and recognize N-degrons". Mol Cell Biol. 25 (16): 7120–7136. doi:10.1128/MCB.25.16.7120-7136.2005. PMC 1190250. PMID 16055722.
^ "Entrez Gene: ZUBR1 zinc finger, UBR1 type 1".
^ "UniProt, Q5T4S7" (jezik: eng.). Pristupljeno 1. 12. 2021.CS1 održavanje: nepoznati jezik (link)

Dopunska literatura[uredi | uredi izvor]

Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction". Anal. Biochem. 236 (1): 107–113. doi:10.1006/abio.1996.0138. PMID 8619474.
Yu W, Andersson B, Worley KC, et al. (1997). "Large-scale concatenation cDNA sequencing". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146. PMID 9110174.
Seki N, Ohira M, Nagase T, et al. (1998). "Characterization of cDNA clones in size-fractionated cDNA libraries from human brain". DNA Res. 4 (5): 345–349. doi:10.1093/dnares/4.5.345. PMID 9455484.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–16903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Huh KW, DeMasi J, Ogawa H, et al. (2005). "Association of the human papillomavirus type 16 E7 oncoprotein with the 600-kDa retinoblastoma protein-associated factor, p600". Proc. Natl. Acad. Sci. U.S.A. 102 (32): 11492–11497. Bibcode:2005PNAS..10211492H. doi:10.1073/pnas.0505337102. PMC 1182135. PMID 16061792.
Nakatani Y, Konishi H, Vassilev A, et al. (2005). "p600, a unique protein required for membrane morphogenesis and cell survival". Proc. Natl. Acad. Sci. U.S.A. 102 (42): 15093–15098. doi:10.1073/pnas.0507458102. PMC 1247991. PMID 16214886.
Lennerz V, Fatho M, Gentilini C, et al. (2005). "The response of autologous T cells to a human melanoma is dominated by mutated neoantigens". Proc. Natl. Acad. Sci. U.S.A. 102 (44): 16013–16018. Bibcode:2005PNAS..10216013L. doi:10.1073/pnas.0500090102. PMC 1266037. PMID 16247014.
Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.

Vanjski linkovi[uredi | uredi izvor]

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000127481 - Ensembl, maj 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000066036 - Ensembl, maj 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid14702039-5] Ota T, Suzuki Y, Nishikawa T, Otsuki T, Sugiyama T, Irie R, Wakamatsu A, Hayashi K, Sato H, Nagai K, Kimura K, Makita H, Sekine M, Obayashi M, Nishi T, Shibahara T, Tanaka T, Ishii S, Yamamoto J, Saito K, Kawai Y, Isono Y, Nakamura Y, Nagahari K, Murakami K, Yasuda T, Iwayanagi T, Wagatsuma M, Shiratori A, Sudo H, Hosoiri T, Kaku Y, Kodaira H, Kondo H, Sugawara M, Takahashi M, Kanda K, Yokoi T, Furuya T, Kikkawa E, Omura Y, Abe K, Kamihara K, Katsuta N, Sato K, Tanikawa M, Yamazaki M, Ninomiya K, Ishibashi T, Yamashita H, Murakawa K, Fujimori K, Tanai H, Kimata M, Watanabe M, Hiraoka S, Chiba Y, Ishida S, Ono Y, Takiguchi S, Watanabe S, Yosida M, Hotuta T, Kusano J, Kanehori K, Takahashi-Fujii A, Hara H, Tanase TO, Nomura Y, Togiya S, Komai F, Hara R, Takeuchi K, Arita M, Imose N, Musashino K, Yuuki H, Oshima A, Sasaki N, Aotsuka S, Yoshikawa Y, Matsunawa H, Ichihara T, Shiohata N, Sano S, Moriya S, Momiyama H, Satoh N, Takami S, Terashima Y, Suzuki O, Nakagawa S, Senoh A, Mizoguchi H, Goto Y, Shimizu F, Wakebe H, Hishigaki H, Watanabe T, Sugiyama A, Takemoto M, Kawakami B, Yamazaki M, Watanabe K, Kumagai A, Itakura S, Fukuzumi Y, Fujimori Y, Komiyama M, Tashiro H, Tanigami A, Fujiwara T, Ono T, Yamada K, Fujii Y, Ozaki K, Hirao M, Ohmori Y, Kawabata A, Hikiji T, Kobatake N, Inagaki H, Ikema Y, Okamoto S, Okitani R, Kawakami T, Noguchi S, Itoh T, Shigeta K, Senba T, Matsumura K, Nakajima Y, Mizuno T, Morinaga M, Sasaki M, Togashi T, Oyama M, Hata H, Watanabe M, Komatsu T, Mizushima-Sugano J, Satoh T, Shirai Y, Takahashi Y, Nakagawa K, Okumura K, Nagase T, Nomura N, Kikuchi H, Masuho Y, Yamashita R, Nakai K, Yada T, Nakamura Y, Ohara O, Isogai T, Sugano S (Dec 2003). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat Genet. 36 (1): 40–45. doi:10.1038/ng1285. PMID 14702039.

[pmid10718198-6] Nagase T, Kikuno R, Ishikawa KI, Hirosawa M, Ohara O (Apr 2000). "Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 7 (1): 65–73. doi:10.1093/dnares/7.1.65. PMID 10718198.

[pmid16055722-7] Tasaki T, Mulder LC, Iwamatsu A, Lee MJ, Davydov IV, Varshavsky A, Muesing M, Kwon YT (Aug 2005). "A family of mammalian E3 ubiquitin ligases that contain the UBR box motif and recognize N-degrons". Mol Cell Biol. 25 (16): 7120–7136. doi:10.1128/MCB.25.16.7120-7136.2005. PMC 1190250. PMID 16055722.

[entrez-8] "Entrez Gene: ZUBR1 zinc finger, UBR1 type 1".

[UniProt-9] "UniProt, Q5T4S7" (jezik: eng.). Pristupljeno 1. 12. 2021.CS1 održavanje: nepoznati jezik (link)

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p r u Enzimi
Teme	Aktivno mjesto Alosterna regulacija Difuzijski limitirani enzim EC broj Enzimska kataliza Inhibicija enzimskih reakcija Kinetika enzima Koenzim Kooperativnost Lineweaver–Burkov dijagram Michaelis–Mentenova kinetika Mjesto vezanja Spisak enzima
Tipovi	EC1 Oksidoreduktaze/spisak EC2 Transferaze/spisak EC3 Hidrolaze/spisak EC4 Lijaze/spisak EC5 Izomeraze/spisak EC6 Ligaze/spisak